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DATA-ADAPTIVE EFFICIENT ESTIMATION STRATEGIES FOR BIOMARKER STUDIES EMBEDDED IN RANDOMIZED TRIALS 期刊论文
ANNALS OF APPLIED STATISTICS, 2022, 卷号: 16, 期号: 4, 页码: 2250-2265
作者:  Zhang, Weiz;  Zhang, Zhi wei;  Troendle, James F.;  Liu, Aiyi
收藏  |  浏览/下载：59/0  |  提交时间：2023/02/07
Augmentation  precision medicine  semiparametric theory  super learner  two-phase sampling  
Biomarker interaction selection and disease detection based on multivariate gain ratio 期刊论文
BMC BIOINFORMATICS, 2022, 卷号: 23, 期号: 1, 页码: 16
作者:  Chu, Xiao;  Jiang, Mao;  Liu, Zhuo-Jun
收藏  |  浏览/下载：55/0  |  提交时间：2023/02/07
Multivariate gain ratio  Biomarker interaction  Disease detection  
hDirect-MAP: projection-free single-cell modeling of response to checkpoint immunotherapy 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2022, 卷号: 23, 期号: 2, 页码: 16
作者:  Lu, Yong;  Xue, Gang;  Zheng, Ningbo;  Han, Kun;  Yang, Wenzhong;  Wang, Rui-Sheng;  Wu, Lingyun;  Miller, Lance D.;  Pardee, Timothy;  Triozzi, Pierre L.;  Lo, Hui-Wen;  Watabe, Kounosuke;  Wong, Stephen T. C.;  Pasche, Boris C.;  Zhang, Wei;  Jin, Guangxu
收藏  |  浏览/下载：126/0  |  提交时间：2023/02/07
single-cell RNA sequencing (scRNA-seq)  single-cell mass cytometry (CyTOF)  Pareto optimization  projection-free single-cell modeling  response to immune checkpoint blockade  
Group testing can improve the cost-efficiency of prospective-retrospective biomarker studies 期刊论文
BMC MEDICAL RESEARCH METHODOLOGY, 2021, 卷号: 21, 期号: 1, 页码: 10
作者:  Zhang, Wei;  Zhang, Zhiwei;  Krushkal, Julia;  Liu, Aiyi
收藏  |  浏览/下载：135/0  |  提交时间：2021/04/26
Biomarker study design  Cost-efficiency  Group testing  Pooling  Two-phase sampling  
Error-corrected estimation of a diagnostic accuracy index of a biomarker against a continuous gold standard 期刊论文
STATISTICS IN MEDICINE, 2020, 页码: 25
作者:  Wu, Mixia;  Zhang, Xiaoyu;  Zhang, Wei;  Zhang, Xu;  Liu, Aiyi
收藏  |  浏览/下载：131/0  |  提交时间：2021/01/14
adaptive estimation  additive errors  asymptotic normality  biomarkers  diagnostic accuracy  measurement errors  reliability coefficient  
A Branch Point on Differentiation Trajectory is the Bifurcating Event Revealed by Dynamical Network Biomarker Analysis of Single-Cell Data 期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2020, 卷号: 17, 期号: 2, 页码: 366-375
作者:  Chen, Ziwei;  Bai, Xiangqi;  Ma, Liang;  Wang, Xiawei;  Liu, Xiuqin;  Liu, Yuting;  Chen, Luonan;  Wan, Lin
收藏  |  浏览/下载：176/0  |  提交时间：2020/05/24
Trajectory  Heuristic algorithms  Mice  Correlation  Reactive power  Pseudo temporal trajectory  branch point  DNB theory  reconstruction  single-cell data  bifurcation  dynamical system  
Associating lncRNAs with small molecules via bilevel optimization reveals cancer-related lncRNAs 期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2019, 卷号: 15, 期号: 12, 页码: 20
作者:  Wang, Yongcui;  Chen, Shilong;  Chen, Luonan;  Wang, Yong
收藏  |  浏览/下载：185/0  |  提交时间：2020/05/24
Discovering cooperative biomarkers for heterogeneous complex disease diagnoses 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2019, 卷号: 20, 期号: 1, 页码: 89-101
作者:  Sun, Duanchen;  Ren, Xianwen;  Ari, Eszter;  Korcsmaros, Tamas;  Csermely, Peter;  Wu, Ling-Yun
收藏  |  浏览/下载：294/0  |  提交时间：2019/03/05
heterogeneous diseases  cancer biomarker  network-based  cooperative biomarker  gene expression  
Network-Regularized Sparse Logistic Regression Models for Clinical Risk Prediction and Biomarker Discovery 期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2018, 卷号: 15, 期号: 3, 页码: 944-953
作者:  Min, Wenwen;  Liu, Juan;  Zhang, Shihua
收藏  |  浏览/下载：250/0  |  提交时间：2018/07/30
Sparse logistic regression  network-regularized penalty  survival risk prediction  feature selection  
A novel computational model based on super-disease and miRNA for potential miRNA-disease association prediction 期刊论文
MOLECULAR BIOSYSTEMS, 2017, 卷号: 13, 期号: 6, 页码: 1202-1212
作者:  Chen, Xing;  Jiang, Zhi-Chao;  Xie, Di;  Huang, De-Shuang;  Zhao, Qi;  Yan, Gui-Ying;  You, Zhu-Hong
收藏  |  浏览/下载：147/0  |  提交时间：2018/07/30