KMS Of Academy of mathematics and systems sciences, CAS
Error-corrected estimation of a diagnostic accuracy index of a biomarker against a continuous gold standard | |
Wu, Mixia1; Zhang, Xiaoyu1; Zhang, Wei2; Zhang, Xu1; Liu, Aiyi3 | |
2020-11-27 | |
发表期刊 | STATISTICS IN MEDICINE |
ISSN | 0277-6715 |
页码 | 25 |
摘要 | This article concerns evaluating the effectiveness of a continuous diagnostic biomarker against a continuous gold standard that is measured with error. Extending the work of Obuchowski (2005, 2016), Wu et al (2016) suggested an accuracy index and proposed an estimator for the index with error-prone standard when the reliability coefficient is known. Combining with additional measurements (without measurement errors) on the continuous gold standard collected from some subjects, this article proposes two adaptive estimators of the accuracy index when the reliability coefficient is unknown, and further establish the consistency and asymptotic normality of these estimators. Simulation studies are conducted to compare various estimators. Data from an intervention trial on glycemic control among children with type 1 diabetes are used to illustrate the proposed methods. |
关键词 | adaptive estimation additive errors asymptotic normality biomarkers diagnostic accuracy measurement errors reliability coefficient |
DOI | 10.1002/sim.8818 |
收录类别 | SCI |
语种 | 英语 |
资助项目 | Intramural Research Program of the Eunice Kennedy Shriver National Institute of Child Health and Human Development |
WOS研究方向 | Mathematical & Computational Biology ; Public, Environmental & Occupational Health ; Medical Informatics ; Research & Experimental Medicine ; Mathematics |
WOS类目 | Mathematical & Computational Biology ; Public, Environmental & Occupational Health ; Medical Informatics ; Medicine, Research & Experimental ; Statistics & Probability |
WOS记录号 | WOS:000593002800001 |
出版者 | WILEY |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.amss.ac.cn/handle/2S8OKBNM/52505 |
专题 | 中国科学院数学与系统科学研究院 |
通讯作者 | Liu, Aiyi |
作者单位 | 1.Beijing Univ Technol, Coll Stat & Data Sci, Beijing, Peoples R China 2.Chinese Acad Sci, Acad Math & Syst Sci, NCMIS, LSC, Beijing, Peoples R China 3.Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Biostat & Bioinformat Branch, NIH, Bethesda, MD USA |
推荐引用方式 GB/T 7714 | Wu, Mixia,Zhang, Xiaoyu,Zhang, Wei,et al. Error-corrected estimation of a diagnostic accuracy index of a biomarker against a continuous gold standard[J]. STATISTICS IN MEDICINE,2020:25. |
APA | Wu, Mixia,Zhang, Xiaoyu,Zhang, Wei,Zhang, Xu,&Liu, Aiyi.(2020).Error-corrected estimation of a diagnostic accuracy index of a biomarker against a continuous gold standard.STATISTICS IN MEDICINE,25. |
MLA | Wu, Mixia,et al."Error-corrected estimation of a diagnostic accuracy index of a biomarker against a continuous gold standard".STATISTICS IN MEDICINE (2020):25. |
条目包含的文件 | 条目无相关文件。 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论