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MUREN: a robust and multi-reference approach of RNA-seq transcript normalization 期刊论文
BMC Bioinformatics, 2021, 卷号: 22, 期号: 1
Authors:  Feng,Yance;  Li,Lei M.
Favorite  |  View/Download:5/0  |  Submit date:2021/10/26
RNA-seq  Normalization  Asymmetrically regulated transcription profiles (ART)  Skewness  Mode  Multi-reference  
OpenAnnotate: a web server to annotate the chromatin accessibility of genomic regions 期刊论文
NUCLEIC ACIDS RESEARCH, 2021, 卷号: 49, 期号: W1, 页码: W483-W490
Authors:  Chen, Shengquan;  Liu, Qiao;  Cui, Xuejian;  Feng, Zhanying;  Li, Chunquan;  Wang, Xiaowo;  Zhang, Xuegong;  Wang, Yong;  Jiang, Rui
Favorite  |  View/Download:8/0  |  Submit date:2021/10/26
A kernel non-negative matrix factorization framework for single cell clustering 期刊论文
APPLIED MATHEMATICAL MODELLING, 2021, 卷号: 90, 页码: 875-888
Authors:  Jiang, Hao;  Yi, Ming;  Zhang, Shihua
Favorite  |  View/Download:18/0  |  Submit date:2021/04/26
Single cell RNA-sequencing  Kernel non-negative matrix factorization  Cellular heterogeneity  
Imputing single-cell RNA-seq data by considering cell heterogeneity and prior expression of dropouts 期刊论文
JOURNAL OF MOLECULAR CELL BIOLOGY, 2021, 卷号: 13, 期号: 1, 页码: 29-40
Authors:  Zhang, Lihua;  Zhang, Shihua
Favorite  |  View/Download:10/0  |  Submit date:2021/10/26
single-cell RNA-seq  dropout  imputation  low-rank  systems biology  
NeuralEE: A GPU-Accelerated Elastic Embedding Dimensionality Reduction Method for Visualizing Large-Scale scRNA-Seq Data 期刊论文
FRONTIERS IN GENETICS, 2020, 卷号: 11, 页码: 8
Authors:  Xiong, Jiankang;  Gong, Fuzhou;  Wan, Lin;  Ma, Liang
Favorite  |  View/Download:24/0  |  Submit date:2021/01/14
single-cell RNA sequencing  elastic embedding  neural networks  large-scale  stochastic optimization  parametric models  generalizable models  
Unsupervised topological alignment for single-cell multi-omics integration 期刊论文
BIOINFORMATICS, 2020, 卷号: 36, 页码: 48-56
Authors:  Cao, Kai;  Bai, Xiangqi;  Hong, Yiguang;  Wan, Lin
Favorite  |  View/Download:12/0  |  Submit date:2021/01/14
RobustClone: a robust PCA method for tumor clone and evolution inference from single-cell sequencing data 期刊论文
BIOINFORMATICS, 2020, 卷号: 36, 期号: 11, 页码: 3299-3306
Authors:  Chen, Ziwei;  Gong, Fuzhou;  Wan, Lin;  Ma, Liang
Favorite  |  View/Download:43/0  |  Submit date:2020/09/23
scTIM: seeking cell-type-indicative marker from single cell RNA-seq data by consensus optimization 期刊论文
BIOINFORMATICS, 2020, 卷号: 36, 期号: 8, 页码: 2474-2485
Authors:  Feng, Zhanying;  Ren, Xianwen;  Fang, Yuan;  Yin, Yining;  Huang, Chutian;  Zhao, Yimin;  Wang, Yong
Favorite  |  View/Download:47/0  |  Submit date:2020/06/30
Time course regulatory analysis based on paired expression and chromatin accessibility data 期刊论文
GENOME RESEARCH, 2020, 卷号: 30, 期号: 4, 页码: 622-634
Authors:  Duren, Zhana;  Chen, Xi;  Xin, Jingxue;  Wang, Yong;  Wong, Wing Hung
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A Branch Point on Differentiation Trajectory is the Bifurcating Event Revealed by Dynamical Network Biomarker Analysis of Single-Cell Data 期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2020, 卷号: 17, 期号: 2, 页码: 366-375
Authors:  Chen, Ziwei;  Bai, Xiangqi;  Ma, Liang;  Wang, Xiawei;  Liu, Xiuqin;  Liu, Yuting;  Chen, Luonan;  Wan, Lin
Favorite  |  View/Download:32/0  |  Submit date:2020/05/24
Trajectory  Heuristic algorithms  Mice  Correlation  Reactive power  Pseudo temporal trajectory  branch point  DNB theory  reconstruction  single-cell data  bifurcation  dynamical system