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Discovering cooperative biomarkers for heterogeneous complex disease diagnoses 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2019, 卷号: 20, 期号: 1, 页码: 89-101
作者:  Sun, Duanchen;  Ren, Xianwen;  Ari, Eszter;  Korcsmaros, Tamas;  Csermely, Peter;  Wu, Ling-Yun
收藏  |  浏览/下载：294/0  |  提交时间：2019/03/05
heterogeneous diseases  cancer biomarker  network-based  cooperative biomarker  gene expression  
Matrix Integrative Analysis (MIA) of Multiple Genomic Data for Modular Patterns 期刊论文
FRONTIERS IN GENETICS, 2018, 卷号: 9, 页码: 12
作者:  Chen, Jinyu;  Zhang, Shihua
收藏  |  浏览/下载：176/0  |  提交时间：2018/07/30
bioinformatics  multi-dimensional genomics  matrix integrative analysis  data integration  module discovery  non-negative matrix factorization (NMF)  partial least squares (PLS)  
NetGen: a novel network-based probabilistic generative model for gene set functional enrichment analysis 期刊论文
BMC SYSTEMS BIOLOGY, 2017, 卷号: 11, 页码: 14
作者:  Sun, Duanchen;  Liu, Yinliang;  Zhang, Xiang-Sun;  Wu, Ling-Yun
收藏  |  浏览/下载：134/0  |  提交时间：2018/07/30
Gene ontology  Enrichment analysis  Network-based probabilistic generative model  Integer programming  Complex diseases  
Integrative cancer genomics: models, algorithms and analysis 期刊论文
FRONTIERS OF COMPUTER SCIENCE, 2017, 卷号: 11, 期号: 3, 页码: 392-406
作者:  Chen, Jinyu;  Zhang, Shihua
收藏  |  浏览/下载：134/0  |  提交时间：2018/07/30
cancer genomics  model  algorithm  data integration  bioinformatics  computational biology  
Gly-PseAAC: Identifying protein lysine glycation through sequences 期刊论文
GENE, 2017, 卷号: 602, 页码: 1-7
作者:  Xu, Yan;  Li, Li;  Ding, Jun;  Wu, Ling-Yun;  Mai, Guoqin;  Zhou, Fengfeng
收藏  |  浏览/下载：164/0  |  提交时间：2018/07/30
Glycation  Amino acid propensity  Support Vector Machine  
Structure alignment-based classification of RNA-binding pockets reveals regional RNA recognition motifs on protein surfaces 期刊论文
BMC BIOINFORMATICS, 2017, 卷号: 18, 页码: 13
作者:  Liu, Zhi-Ping;  Liu, Shutang;  Chen, Ruitang;  Huang, Xiaopeng;  Wu, Ling-Yun
收藏  |  浏览/下载：149/0  |  提交时间：2018/07/30
RNA-binding pocket  Local structure classification  Structural alignment  Network clustering  Structure motif  
Quantitative function and algorithm for community detection in bipartite networks 期刊论文
INFORMATION SCIENCES, 2016, 卷号: 367, 页码: 874-889
作者:  Li, Zhenping;  Wang, Rui-Sheng;  Zhang, Shihua;  Zhang, Xiang-Sun
收藏  |  浏览/下载：169/0  |  提交时间：2018/07/30
Bipartite network  Community  Quantitative function  Integer programming  Label propagation algorithm  
An integrative and comparative study of pan-cancer transcriptomes reveals distinct cancer common and specific signatures 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6, 页码: 13
作者:  Cao, Zhen;  Zhang, Shihua
收藏  |  浏览/下载：132/0  |  提交时间：2018/07/30
Local community extraction in directed networks 期刊论文
PHYSICA A-STATISTICAL MECHANICS AND ITS APPLICATIONS, 2016, 卷号: 452, 页码: 258-265
作者:  Ning, Xuemei;  Liu, Zhaoqi;  Zhang, Shihua
收藏  |  浏览/下载：135/0  |  提交时间：2018/07/30
Complex network  Community structure  Clustering  Optimization  
Integrative analysis for identifying joint modular patterns of gene-expression and drug-response data 期刊论文
BIOINFORMATICS, 2016, 卷号: 32, 期号: 11, 页码: 1724-1732
作者:  Chen, Jinyu;  Zhang, Shihua
收藏  |  浏览/下载：142/0  |  提交时间：2018/07/30