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Joint reconstruction of cis-regulatory interaction networks across multiple tissues using single-cell chromatin accessibility data 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2021, 卷号: 22, 期号: 3, 页码: 15
作者:  Dong, Kangning;  Zhang, Shihua
收藏  |  浏览/下载：116/0  |  提交时间：2022/04/02
cis-regulatory interaction networks  single-cell ATAC-seq  Gaussian graphical LASSO  
Towards understanding residual and dilated dense neural networks via convolutional sparse coding 期刊论文
NATIONAL SCIENCE REVIEW, 2021, 卷号: 8, 期号: 3, 页码: 13
作者:  Zhang, Zhiyang;  Zhang, Shihua
收藏  |  浏览/下载：150/0  |  提交时间：2021/10/26
convolutional neural network  convolutional sparse coding  residual neural network  mixed-scale dense neural network  dilated convolution  dense connection  
An Integrative Framework for Combining Sequence and Epigenomic Data to Predict Transcription Factor Binding Sites Using Deep Learning 期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2021, 卷号: 18, 期号: 1, 页码: 355-364
作者:  Jing, Fang;  Zhang, Shao-Wu;  Cao, Zhen;  Zhang, Shihua
收藏  |  浏览/下载：176/0  |  提交时间：2021/04/26
Bioinformatics  machine learning  transcription factors binding sites  convolutional neural networks  DNA accessibility  histone modification  
A General Joint Matrix Factorization Framework for Data Integration and Its Systematic Algorithmic Exploration 期刊论文
IEEE TRANSACTIONS ON FUZZY SYSTEMS, 2020, 卷号: 28, 期号: 9, 页码: 1971-1983
作者:  Zhang, Lihua;  Zhang, Shihua
收藏  |  浏览/下载：150/0  |  提交时间：2021/01/14
Sparse matrices  Pattern recognition  Data integration  Prediction algorithms  Data models  Matrix decomposition  Signal processing algorithms  Bioinformatics  data integration  network-regularized constraint  nonnegative matrix factorization (NMF)  pattern recognition  
Probe Efficient Feature Representation of Gapped K-mer Frequency Vectors from Sequences Using Deep Neural Networks 期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2020, 卷号: 17, 期号: 2, 页码: 657-667
作者:  Cao, Zhen;  Zhang, Shihua
收藏  |  浏览/下载：194/0  |  提交时间：2020/05/24
DNA  Bioinformatics  Kernel  Feature extraction  Support vector machines  Genomics  Task analysis  Bioinformatics  machine learning  gapped k-mer  deep neural network  transcription factor binding site prediction  
Simple tricks of convolutional neural network architectures improve DNA-protein binding prediction 期刊论文
BIOINFORMATICS, 2019, 卷号: 35, 期号: 11, 页码: 1837-1843
作者:  Cao, Zhen;  Zhang, Shihua
收藏  |  浏览/下载：191/0  |  提交时间：2020/01/10
Edge-group sparse PCA for network-guided high dimensional data analysis 期刊论文
BIOINFORMATICS, 2018, 卷号: 34, 期号: 20, 页码: 3479-3487
作者:  Min, Wenwen;  Liu, Juan;  Zhang, Shihua
收藏  |  浏览/下载：190/0  |  提交时间：2019/01/11
Integrative Analysis of Transcription Factor Combinatorial Interactions Using a Bayesian Tensor Factorization Approach 期刊论文
FRONTIERS IN GENETICS, 2017, 卷号: 8, 页码: 12
作者:  Ye, Yusen;  Gao, Lin;  Zhang, Shihua
收藏  |  浏览/下载：157/0  |  提交时间：2018/07/30
transcription regulation  TF regulatory networks  tensor factorization  integrative analysis of omics data  biological networks