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RobustClone: a robust PCA method for tumor clone and evolution inference from single-cell sequencing data 期刊论文
BIOINFORMATICS, 2020, 卷号: 36, 期号: 11, 页码: 3299-3306
Authors:  Chen, Ziwei;  Gong, Fuzhou;  Wan, Lin;  Ma, Liang
Favorite  |  View/Download:5/0  |  Submit date:2020/09/23
Probe Efficient Feature Representation of Gapped K-mer Frequency Vectors from Sequences Using Deep Neural Networks 期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2020, 卷号: 17, 期号: 2, 页码: 657-667
Authors:  Cao, Zhen;  Zhang, Shihua
Favorite  |  View/Download:6/0  |  Submit date:2020/05/24
DNA  Bioinformatics  Kernel  Feature extraction  Support vector machines  Genomics  Task analysis  Bioinformatics  machine learning  gapped k-mer  deep neural network  transcription factor binding site prediction  
DC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data 期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 11
Authors:  Zeng, Wanwen;  Chen, Xi;  Duren, Zhana;  Wang, Yong;  Jiang, Rui;  Wong, Wing Hung
Favorite  |  View/Download:11/0  |  Submit date:2020/01/10
Multi-scale analysis of schizophrenia risk genes, brain structure, and clinical symptoms reveals integrative clues for subtyping schizophrenia patients 期刊论文
JOURNAL OF MOLECULAR CELL BIOLOGY, 2019, 卷号: 11, 期号: 8, 页码: 678-687
Authors:  Ma, Liang;  Rolls, Edmund T.;  Liu, Xiuqin;  Liu, Yuting;  Jiao, Zeyu;  Wang, Yue;  Gong, Weikang;  Ma, Zhiming;  Gong, Fuzhou;  Wan, Lin
Favorite  |  View/Download:7/0  |  Submit date:2020/05/24
Schizophrenia  PANSS  multi-scale analysis  hot cluster  grey matter volume  pathway  
A theoretic study of a distance-based regression model 期刊论文
SCIENCE CHINA-MATHEMATICS, 2019, 卷号: 62, 期号: 5, 页码: 979-998
Authors:  Li, Jialu;  Zhang, Wei;  Zhang, Sanguo;  Li, Qizhai
Favorite  |  View/Download:16/0  |  Submit date:2020/01/10
distance-based regression  Euclidean  pseudo F test statistic  Mahalanobis  
TSEE: an elastic embedding method to visualize the dynamic gene expression patterns of time series single-cell RNA sequencing data 期刊论文
BMC GENOMICS, 2019, 卷号: 20, 页码: 16
Authors:  An, Shaokun;  Ma, Liang;  Wan, Lin
Favorite  |  View/Download:14/0  |  Submit date:2019/10/28
Nonlinear dimensionality reduction  Elastic embedding  Visualization  Single-cell RNA sequencing  Time series  Cell fate decisions  Gene expression pattern  Oscillation  In-group proportion  
Prediction of Driver Modules via Balancing Exclusive Coverages of Mutations in Cancer Samples 期刊论文
ADVANCED SCIENCE, 2019, 卷号: 6, 期号: 4, 页码: 9
Authors:  Gao, Bo;  Zhao, Yue;  Li, Yang;  Liu, Juntao;  Wang, Lushan;  Li, Guojun;  Su, Zhengchang
Favorite  |  View/Download:19/0  |  Submit date:2019/04/02
cancer genomics  coverage  driver modules  exclusivity  signaling networks  
multiscaleanalysisofschizophreniariskgenesbrainstructureandclinicalsymptomsrevealsintegrativecluesforsubtypingschizophreniapatients 期刊论文
journalofmolecularcellbiology, 2019, 卷号: 11, 期号: 8, 页码: 678-687
Authors:  Ma Liang;  Rolls Edmund T;  Liu Xiuqin;  Liu Yuting;  Jiao Zeyu;  Wang Yue;  Gong Weikang;  Ma Zhiming;  Gong Fuzhou;  Wan Lin
Favorite  |  View/Download:5/0  |  Submit date:2020/05/24
atheoreticstudyofadistancebasedregressionmodel 期刊论文
中国科学数学英文版, 2019, 卷号: 000, 期号: 005, 页码: 979
Authors:  Jialu Li;  Wei Zhang;  Sanguo Zhang;  Qizhai Li
Favorite  |  View/Download:14/0  |  Submit date:2020/01/10
Reveal cell type-specific regulatory elements and their characterized histone code classes via a hidden Markov model 期刊论文
BMC GENOMICS, 2018, 卷号: 19, 页码: 13
Authors:  Wang, Can;  Zhang, Shihua
Favorite  |  View/Download:20/0  |  Submit date:2019/01/11
Epigenomics  Cell type-specific regulatory elements  Hidden Markov model  Histone modification