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The cis-trans binding strength defined by motif frequencies facilitates statistical inference of transcriptional regulation 期刊论文
BMC Bioinformatics, 2019, 卷号: 20, 期号: Suppl 7
Authors:  Feng,Yance;  Zhang,Sheng;  Li,Liang;  Li,Lei M.
Favorite  |  View/Download:0/0  |  Submit date:2019/10/28
BASE  Statistical inference  Transcriptional regulation  PUFA  DHA  EPA  Binding strength  
Systems biology intertwines with single cell and AI 期刊论文
BMC Bioinformatics, 2019, 卷号: 20, 期号: Suppl 7
Authors:  Wang,Yong;  Zhang,Xiang-Sun;  Chen,Luonan
Favorite  |  View/Download:0/0  |  Submit date:2019/10/28
Systems biology  Network  Data integration  
Integrating random walk and binary regression to identify novel miRNA-disease association 期刊论文
BMC BIOINFORMATICS, 2019, 卷号: 20, 页码: 13
Authors:  Niu, Ya-Wei;  Wang, Guang-Hui;  Yan, Gui-Ying;  Chen, Xing
Favorite  |  View/Download:4/0  |  Submit date:2019/03/05
microRNA  Disease  miRNA-disease association  Random walk  Binary regression  
Discovering cooperative biomarkers for heterogeneous complex disease diagnoses 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2019, 卷号: 20, 期号: 1, 页码: 89-101
Authors:  Sun, Duanchen;  Ren, Xianwen;  Ari, Eszter;  Korcsmaros, Tamas;  Csermely, Peter;  Wu, Ling-Yun
Favorite  |  View/Download:3/0  |  Submit date:2019/03/05
heterogeneous diseases  cancer biomarker  network-based  cooperative biomarker  gene expression  
Brief Survey of Biological Network Alignment and a Variant with Incorporation of Functional Annotations 期刊论文
CURRENT BIOINFORMATICS, 2019, 卷号: 14, 期号: 1, 页码: 4-10
Authors:  Jing, Fang;  Zhang, Shao-Wu;  Zhang, Shihua
Favorite  |  View/Download:4/0  |  Submit date:2019/04/02
Biological network  network alignment  gene ontology  alignment graph  optimization  
Edge-group sparse PCA for network-guided high dimensional data analysis 期刊论文
BIOINFORMATICS, 2018, 卷号: 34, 期号: 20, 页码: 3479-3487
Authors:  Min, Wenwen;  Liu, Juan;  Zhang, Shihua
Favorite  |  View/Download:3/0  |  Submit date:2019/01/11
CEA: Combination-based gene set functional enrichment analysis 期刊论文
SCIENTIFIC REPORTS, 2018, 卷号: 8, 页码: 13
Authors:  Sun, Duanchen;  Liu, Yinliang;  Zhang, Xiang-Sun;  Wu, Ling-Yun
Favorite  |  View/Download:8/0  |  Submit date:2018/10/07
BAUM: improving genome assembly by adaptive unique mapping and local overlap-layout-consensus approach 期刊论文
BIOINFORMATICS, 2018, 卷号: 34, 期号: 12, 页码: 2019-2028
Authors:  Wang, Anqi;  Wang, Zhanyu;  Li, Zheng;  Li, Lei M.
Favorite  |  View/Download:8/0  |  Submit date:2018/07/30
Matrix Integrative Analysis (MIA) of Multiple Genomic Data for Modular Patterns 期刊论文
FRONTIERS IN GENETICS, 2018, 卷号: 9, 页码: 12
Authors:  Chen, Jinyu;  Zhang, Shihua
Favorite  |  View/Download:6/0  |  Submit date:2018/07/30
bioinformatics  multi-dimensional genomics  matrix integrative analysis  data integration  module discovery  non-negative matrix factorization (NMF)  partial least squares (PLS)  
Network-Regularized Sparse Logistic Regression Models for Clinical Risk Prediction and Biomarker Discovery 期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2018, 卷号: 15, 期号: 3, 页码: 944-953
Authors:  Min, Wenwen;  Liu, Juan;  Zhang, Shihua
Favorite  |  View/Download:6/0  |  Submit date:2018/07/30
Sparse logistic regression  network-regularized penalty  survival risk prediction  feature selection