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Prediction of the transcription factor binding sites with meta-learning 期刊论文
METHODS, 2022, 卷号: 203, 页码: 207-213
作者:  Jing, Fang;  Zhang, Shao-Wu;  Zhang, Shihua
收藏  |  浏览/下载：212/0  |  提交时间：2023/02/07
Convolution neural network  Transcription factor binding sites  Meta learning  Noisy labels data  
An Integrative Framework for Combining Sequence and Epigenomic Data to Predict Transcription Factor Binding Sites Using Deep Learning 期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2021, 卷号: 18, 期号: 1, 页码: 355-364
作者:  Jing, Fang;  Zhang, Shao-Wu;  Cao, Zhen;  Zhang, Shihua
收藏  |  浏览/下载：193/0  |  提交时间：2021/04/26
Bioinformatics  machine learning  transcription factors binding sites  convolutional neural networks  DNA accessibility  histone modification  
Prediction of enhancer-promoter interactions using the cross-cell type information and domain adversarial neural network 期刊论文
BMC BIOINFORMATICS, 2020, 卷号: 21, 期号: 1, 页码: 16
作者:  Jing, Fang;  Zhang, Shao-Wu;  Zhang, Shihua
收藏  |  浏览/下载：155/0  |  提交时间：2021/01/14
Enhancer–  promoter interactions  Cell line  Convolutional neural network  Transfer learning  Gradient reversal layer  
Prediction of enhancer–promoter interactions using the cross-cell type information and domain adversarial neural network 期刊论文
BMC Bioinformatics, 2020, 卷号: 21, 期号: 1
作者:  Jing,Fang;  Zhang,Shao-Wu;  Zhang,Shihua
收藏  |  浏览/下载：153/0  |  提交时间：2021/01/14
Enhancer–promoter interactions  Cell line  Convolutional neural network  Transfer learning  Gradient reversal layer  
Probe Efficient Feature Representation of Gapped K-mer Frequency Vectors from Sequences Using Deep Neural Networks 期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2020, 卷号: 17, 期号: 2, 页码: 657-667
作者:  Cao, Zhen;  Zhang, Shihua
收藏  |  浏览/下载：207/0  |  提交时间：2020/05/24
DNA  Bioinformatics  Kernel  Feature extraction  Support vector machines  Genomics  Task analysis  Bioinformatics  machine learning  gapped k-mer  deep neural network  transcription factor binding site prediction  
Simple tricks of convolutional neural network architectures improve DNA-protein binding prediction 期刊论文
BIOINFORMATICS, 2019, 卷号: 35, 期号: 11, 页码: 1837-1843
作者:  Cao, Zhen;  Zhang, Shihua
收藏  |  浏览/下载：196/0  |  提交时间：2020/01/10
Matrix Integrative Analysis (MIA) of Multiple Genomic Data for Modular Patterns 期刊论文
FRONTIERS IN GENETICS, 2018, 卷号: 9, 页码: 12
作者:  Chen, Jinyu;  Zhang, Shihua
收藏  |  浏览/下载：192/0  |  提交时间：2018/07/30
bioinformatics  multi-dimensional genomics  matrix integrative analysis  data integration  module discovery  non-negative matrix factorization (NMF)  partial least squares (PLS)  
Comparative pan-cancer DNA methylation analysis reveals cancer common and specific patterns 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2017, 卷号: 18, 期号: 5, 页码: 761-773
作者:  Yang, Xiaofei;  Gao, Lin;  Zhang, Shihua
收藏  |  浏览/下载：147/0  |  提交时间：2018/07/30
cancer genomics  DNA-methylation  pan-cancer study  bioinformatics  
Comparative DNA methylation analysis to decipher common and cell type-specific patterns among multiple cell types 期刊论文
BRIEFINGS IN FUNCTIONAL GENOMICS, 2016, 卷号: 15, 期号: 6, 页码: 399-407
作者:  Yang, Xiaofei;  Shao, Xiaojian;  Gao, Lin;  Zhang, Shihua
收藏  |  浏览/下载：183/0  |  提交时间：2018/07/30
DNA methylation patterns  differentially methylation regions  comparative studies  tissue-specific methylation  cancer epigenomics  
An integrative and comparative study of pan-cancer transcriptomes reveals distinct cancer common and specific signatures 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6, 页码: 13
作者:  Cao, Zhen;  Zhang, Shihua
收藏  |  浏览/下载：142/0  |  提交时间：2018/07/30