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Adversarial Information Bottleneck 期刊论文
IEEE TRANSACTIONS ON NEURAL NETWORKS AND LEARNING SYSTEMS, 2022, 页码: 10
作者:  Zhai, Penglong;  Zhang, Shihua
收藏  |  浏览/下载:56/0  |  提交时间:2023/02/07
Robustness  Optimization  Mutual information  Deep learning  Perturbation methods  Training  Task analysis  Adversarial robustness  deep learning  hyperparameter selection  information bottleneck (IB)  
Deciphering spatial domains from spatially resolved transcriptomics with an adaptive graph attention auto-encoder 期刊论文
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 12
作者:  Dong, Kangning;  Zhang, Shihua
收藏  |  浏览/下载:104/0  |  提交时间:2022/06/21
A Novel Sparse Graph-Regularized Singular Value Decomposition Model and Its Application to Genomic Data Analysis 期刊论文
IEEE TRANSACTIONS ON NEURAL NETWORKS AND LEARNING SYSTEMS, 2021, 页码: 15
作者:  Min, Wenwen;  Wan, Xiang;  Chang, Tsung-Hui;  Zhang, Shihua
收藏  |  浏览/下载:141/0  |  提交时间:2022/04/02
Gene expression  Biology  Biological system modeling  Principal component analysis  Mathematical model  Data models  Big Data  Absolute-valued graph regularization  graph regularization  sparse learning  structured sparse singular value decomposition (SVD)  
Group-Sparse SVD Models via L-1- and L-0-norm Penalties and their Applications in Biological Data 期刊论文
IEEE TRANSACTIONS ON KNOWLEDGE AND DATA ENGINEERING, 2021, 卷号: 33, 期号: 2, 页码: 536-550
作者:  Min, Wenwen;  Liu, Juan;  Zhang, Shihua
收藏  |  浏览/下载:168/0  |  提交时间:2021/04/26
Sparse SVD  low-rank matrix decomposition  group-sparse penalty  overlapping group-sparse penalty  coordinate descent method  alternating direction method of multipliers (ADMM)  data mining  
A kernel non-negative matrix factorization framework for single cell clustering 期刊论文
APPLIED MATHEMATICAL MODELLING, 2021, 卷号: 90, 页码: 875-888
作者:  Jiang, Hao;  Yi, Ming;  Zhang, Shihua
收藏  |  浏览/下载:128/0  |  提交时间:2021/04/26
Single cell RNA-sequencing  Kernel non-negative matrix factorization  Cellular heterogeneity  
Prediction of enhancer-promoter interactions using the cross-cell type information and domain adversarial neural network 期刊论文
BMC BIOINFORMATICS, 2020, 卷号: 21, 期号: 1, 页码: 16
作者:  Jing, Fang;  Zhang, Shao-Wu;  Zhang, Shihua
收藏  |  浏览/下载:143/0  |  提交时间:2021/01/14
Enhancer–  promoter interactions  Cell line  Convolutional neural network  Transfer learning  Gradient reversal layer  
Prediction of enhancer–promoter interactions using the cross-cell type information and domain adversarial neural network 期刊论文
BMC Bioinformatics, 2020, 卷号: 21, 期号: 1
作者:  Jing,Fang;  Zhang,Shao-Wu;  Zhang,Shihua
收藏  |  浏览/下载:147/0  |  提交时间:2021/01/14
Enhancer–promoter interactions  Cell line  Convolutional neural network  Transfer learning  Gradient reversal layer  
Circular Trajectory Reconstruction Uncovers Cell-Cycle Progression and Regulatory Dynamics from Single-Cell Hi-C Maps 期刊论文
ADVANCED SCIENCE, 2019, 页码: 13
作者:  Ye, Yusen;  Gao, Lin;  Zhang, Shihua
收藏  |  浏览/下载:289/0  |  提交时间:2020/01/10
cell cycle  chromosomal architectures  circular trajectory  dynamic structures  single-cell Hi-C maps  
Simple tricks of convolutional neural network architectures improve DNA-protein binding prediction 期刊论文
BIOINFORMATICS, 2019, 卷号: 35, 期号: 11, 页码: 1837-1843
作者:  Cao, Zhen;  Zhang, Shihua
收藏  |  浏览/下载:191/0  |  提交时间:2020/01/10
Brief Survey of Biological Network Alignment and a Variant with Incorporation of Functional Annotations 期刊论文
CURRENT BIOINFORMATICS, 2019, 卷号: 14, 期号: 1, 页码: 4-10
作者:  Jing, Fang;  Zhang, Shao-Wu;  Zhang, Shihua
收藏  |  浏览/下载:183/0  |  提交时间:2019/04/02
Biological network  network alignment  gene ontology  alignment graph  optimization