KMS Of Academy of mathematics and systems sciences, CAS
Brief Survey of Biological Network Alignment and a Variant with Incorporation of Functional Annotations | |
Jing, Fang1; Zhang, Shao-Wu1; Zhang, Shihua2,3![]() | |
2019 | |
发表期刊 | CURRENT BIOINFORMATICS
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ISSN | 1574-8936 |
卷号 | 14期号:1页码:4-10 |
摘要 | Background: Biological network alignment has been widely studied in the context of protein-protein interaction (PPI) networks, metabolic networks and others in bioinformatics. The topological structure of networks and genomic sequence are generally used by existing methods for achieving this task. Objective and Method: Here we briefly survey the methods generally used for this task and introduce a variant with incorporation of functional annotations based on similarity in Gene Ontology (GO). Making full use of GO information is beneficial to provide insights into precise biological network alignment. Results and Conclusion: We analyze the effect of incorporation of GO information to network alignment. Finally, we make a brief summary and discuss future directions about this topic. |
关键词 | Biological network network alignment gene ontology alignment graph optimization |
DOI | 10.2174/1574893612666171020103747 |
语种 | 英语 |
资助项目 | National Natural Science Foundation of China[61873202] ; National Natural Science Foundation of China[61621003] ; National Natural Science Foundation of China[61473232] ; National Natural Science Foundation of China[91430111] |
WOS研究方向 | Biochemistry & Molecular Biology ; Mathematical & Computational Biology |
WOS类目 | Biochemical Research Methods ; Mathematical & Computational Biology |
WOS记录号 | WOS:000458622200002 |
出版者 | BENTHAM SCIENCE PUBL LTD |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.amss.ac.cn/handle/2S8OKBNM/32552 |
专题 | 应用数学研究所 |
通讯作者 | Zhang, Shao-Wu; Zhang, Shihua |
作者单位 | 1.Northwestern Polytech Univ, Coll Automat, Minist Educ, Key Lab Informat Fus Technol, Xian 710072, Shaanxi, Peoples R China 2.Chinese Acad Sci, Acad Math & Syst Sci, RCSDS, CEMS,NCMIS, Beijing 100190, Peoples R China 3.Univ Chinese Acad Sci, Sch Math Sci, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Jing, Fang,Zhang, Shao-Wu,Zhang, Shihua. Brief Survey of Biological Network Alignment and a Variant with Incorporation of Functional Annotations[J]. CURRENT BIOINFORMATICS,2019,14(1):4-10. |
APA | Jing, Fang,Zhang, Shao-Wu,&Zhang, Shihua.(2019).Brief Survey of Biological Network Alignment and a Variant with Incorporation of Functional Annotations.CURRENT BIOINFORMATICS,14(1),4-10. |
MLA | Jing, Fang,et al."Brief Survey of Biological Network Alignment and a Variant with Incorporation of Functional Annotations".CURRENT BIOINFORMATICS 14.1(2019):4-10. |
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