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Brief Survey of Biological Network Alignment and a Variant with Incorporation of Functional Annotations
Jing, Fang1; Zhang, Shao-Wu1; Zhang, Shihua2,3
2019
发表期刊CURRENT BIOINFORMATICS
ISSN1574-8936
卷号14期号:1页码:4-10
摘要Background: Biological network alignment has been widely studied in the context of protein-protein interaction (PPI) networks, metabolic networks and others in bioinformatics. The topological structure of networks and genomic sequence are generally used by existing methods for achieving this task. Objective and Method: Here we briefly survey the methods generally used for this task and introduce a variant with incorporation of functional annotations based on similarity in Gene Ontology (GO). Making full use of GO information is beneficial to provide insights into precise biological network alignment. Results and Conclusion: We analyze the effect of incorporation of GO information to network alignment. Finally, we make a brief summary and discuss future directions about this topic.
关键词Biological network network alignment gene ontology alignment graph optimization
DOI10.2174/1574893612666171020103747
语种英语
资助项目National Natural Science Foundation of China[61873202] ; National Natural Science Foundation of China[61621003] ; National Natural Science Foundation of China[61473232] ; National Natural Science Foundation of China[91430111]
WOS研究方向Biochemistry & Molecular Biology ; Mathematical & Computational Biology
WOS类目Biochemical Research Methods ; Mathematical & Computational Biology
WOS记录号WOS:000458622200002
出版者BENTHAM SCIENCE PUBL LTD
引用统计
文献类型期刊论文
条目标识符http://ir.amss.ac.cn/handle/2S8OKBNM/32552
专题应用数学研究所
通讯作者Zhang, Shao-Wu; Zhang, Shihua
作者单位1.Northwestern Polytech Univ, Coll Automat, Minist Educ, Key Lab Informat Fus Technol, Xian 710072, Shaanxi, Peoples R China
2.Chinese Acad Sci, Acad Math & Syst Sci, RCSDS, CEMS,NCMIS, Beijing 100190, Peoples R China
3.Univ Chinese Acad Sci, Sch Math Sci, Beijing 100049, Peoples R China
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Jing, Fang,Zhang, Shao-Wu,Zhang, Shihua. Brief Survey of Biological Network Alignment and a Variant with Incorporation of Functional Annotations[J]. CURRENT BIOINFORMATICS,2019,14(1):4-10.
APA Jing, Fang,Zhang, Shao-Wu,&Zhang, Shihua.(2019).Brief Survey of Biological Network Alignment and a Variant with Incorporation of Functional Annotations.CURRENT BIOINFORMATICS,14(1),4-10.
MLA Jing, Fang,et al."Brief Survey of Biological Network Alignment and a Variant with Incorporation of Functional Annotations".CURRENT BIOINFORMATICS 14.1(2019):4-10.
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