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Brief Survey of Biological Network Alignment and a Variant with Incorporation of Functional Annotations
Jing, Fang1; Zhang, Shao-Wu1; Zhang, Shihua2,3
2019
Source PublicationCURRENT BIOINFORMATICS
ISSN1574-8936
Volume14Issue:1Pages:4-10
AbstractBackground: Biological network alignment has been widely studied in the context of protein-protein interaction (PPI) networks, metabolic networks and others in bioinformatics. The topological structure of networks and genomic sequence are generally used by existing methods for achieving this task. Objective and Method: Here we briefly survey the methods generally used for this task and introduce a variant with incorporation of functional annotations based on similarity in Gene Ontology (GO). Making full use of GO information is beneficial to provide insights into precise biological network alignment. Results and Conclusion: We analyze the effect of incorporation of GO information to network alignment. Finally, we make a brief summary and discuss future directions about this topic.
KeywordBiological network network alignment gene ontology alignment graph optimization
DOI10.2174/1574893612666171020103747
Language英语
Funding ProjectNational Natural Science Foundation of China[61873202] ; National Natural Science Foundation of China[61621003] ; National Natural Science Foundation of China[61473232] ; National Natural Science Foundation of China[91430111]
WOS Research AreaBiochemistry & Molecular Biology ; Mathematical & Computational Biology
WOS SubjectBiochemical Research Methods ; Mathematical & Computational Biology
WOS IDWOS:000458622200002
PublisherBENTHAM SCIENCE PUBL LTD
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Document Type期刊论文
Identifierhttp://ir.amss.ac.cn/handle/2S8OKBNM/32552
Collection应用数学研究所
Affiliation1.Northwestern Polytech Univ, Coll Automat, Minist Educ, Key Lab Informat Fus Technol, Xian 710072, Shaanxi, Peoples R China
2.Chinese Acad Sci, Acad Math & Syst Sci, RCSDS, CEMS,NCMIS, Beijing 100190, Peoples R China
3.Univ Chinese Acad Sci, Sch Math Sci, Beijing 100049, Peoples R China
Recommended Citation
GB/T 7714
Jing, Fang,Zhang, Shao-Wu,Zhang, Shihua. Brief Survey of Biological Network Alignment and a Variant with Incorporation of Functional Annotations[J]. CURRENT BIOINFORMATICS,2019,14(1):4-10.
APA Jing, Fang,Zhang, Shao-Wu,&Zhang, Shihua.(2019).Brief Survey of Biological Network Alignment and a Variant with Incorporation of Functional Annotations.CURRENT BIOINFORMATICS,14(1),4-10.
MLA Jing, Fang,et al."Brief Survey of Biological Network Alignment and a Variant with Incorporation of Functional Annotations".CURRENT BIOINFORMATICS 14.1(2019):4-10.
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