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Discovering cooperative biomarkers for heterogeneous complex disease diagnoses 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2019, 卷号: 20, 期号: 1, 页码: 89-101
作者:  Sun, Duanchen;  Ren, Xianwen;  Ari, Eszter;  Korcsmaros, Tamas;  Csermely, Peter;  Wu, Ling-Yun
收藏  |  浏览/下载:331/0  |  提交时间:2019/03/05
heterogeneous diseases  cancer biomarker  network-based  cooperative biomarker  gene expression  
Matrix Integrative Analysis (MIA) of Multiple Genomic Data for Modular Patterns 期刊论文
FRONTIERS IN GENETICS, 2018, 卷号: 9, 页码: 12
作者:  Chen, Jinyu;  Zhang, Shihua
收藏  |  浏览/下载:194/0  |  提交时间:2018/07/30
bioinformatics  multi-dimensional genomics  matrix integrative analysis  data integration  module discovery  non-negative matrix factorization (NMF)  partial least squares (PLS)  
NetGen: a novel network-based probabilistic generative model for gene set functional enrichment analysis 期刊论文
BMC SYSTEMS BIOLOGY, 2017, 卷号: 11, 页码: 14
作者:  Sun, Duanchen;  Liu, Yinliang;  Zhang, Xiang-Sun;  Wu, Ling-Yun
收藏  |  浏览/下载:140/0  |  提交时间:2018/07/30
Gene ontology  Enrichment analysis  Network-based probabilistic generative model  Integer programming  Complex diseases  
Integrative cancer genomics: models, algorithms and analysis 期刊论文
FRONTIERS OF COMPUTER SCIENCE, 2017, 卷号: 11, 期号: 3, 页码: 392-406
作者:  Chen, Jinyu;  Zhang, Shihua
收藏  |  浏览/下载:147/0  |  提交时间:2018/07/30
cancer genomics  model  algorithm  data integration  bioinformatics  computational biology  
An integrative and comparative study of pan-cancer transcriptomes reveals distinct cancer common and specific signatures 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6, 页码: 13
作者:  Cao, Zhen;  Zhang, Shihua
收藏  |  浏览/下载:144/0  |  提交时间:2018/07/30
Integrative analysis for identifying joint modular patterns of gene-expression and drug-response data 期刊论文
BIOINFORMATICS, 2016, 卷号: 32, 期号: 11, 页码: 1724-1732
作者:  Chen, Jinyu;  Zhang, Shihua
收藏  |  浏览/下载:154/0  |  提交时间:2018/07/30