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Revealing transcription factor and histone modification co-localization and dynamics across cell lines by integrating ChIP-seq and RNA-seq data 期刊论文
BMC GENOMICS, 2018, 卷号: 19, 页码: 16
作者:  Zhang, Lirong;  Xue, Gaogao;  Liu, Junjie;  Li, Qianzhong;  Wang, Yong
收藏  |  浏览/下载:285/0  |  提交时间:2019/01/11
Transcription factor  Histone modification  Co-localization  Dynamics  
Hybrid method to solve HP model on 3D lattice and to probe protein stability upon amino acid mutations 期刊论文
BMC SYSTEMS BIOLOGY, 2017, 卷号: 11, 页码: 13
作者:  Guo, Yuzhen;  Tao, Fengying;  Wu, Zikai;  Wang, Yong
收藏  |  浏览/下载:175/0  |  提交时间:2018/07/30
Protein structure prediction  HP model  3D lattice  Particle swarm optimization  Protein stability  
Extended particle swarm optimisation method for folding protein on triangular lattice 期刊论文
IET SYSTEMS BIOLOGY, 2016, 卷号: 10, 期号: 1, 页码: 30-33
作者:  Guo, Yuzhen;  Wu, Zikai;  Wang, Ying;  Wang, Yong
收藏  |  浏览/下载:143/0  |  提交时间:2018/07/30
proteins  molecular biophysics  molecular configurations  particle swarm optimisation  bioinformatics  extended particle swarm optimisation method  triangular lattice  protein structure prediction problem  two-dimensional hydrophobic-polar model  noncompact conformation  amino acid sequence  single point adjustment strategy  protein folding  
Computational probing protein-protein interactions targeting small molecules 期刊论文
BIOINFORMATICS, 2016, 卷号: 32, 期号: 2, 页码: 226-234
作者:  Wang, Yong-Cui;  Chen, Shi-Long;  Deng, Nai-Yang;  Wang, Yong
收藏  |  浏览/下载:140/0  |  提交时间:2018/07/30
Rigorous assessment and integration of the sequence and structure based features to predict hot spots 期刊论文
BMC BIOINFORMATICS, 2011, 卷号: 12, 页码: 14
作者:  Chen, Ruoying;  Chen, Wenjing;  Yang, Sixiao;  Wu, Di;  Wang, Yong;  Tian, Yingjie;  Shi, Yong
收藏  |  浏览/下载:141/0  |  提交时间:2018/07/30
Support vector machine prediction of enzyme function with conjoint triad feature and hierarchical context 期刊论文
BMC SYSTEMS BIOLOGY, 2011, 卷号: 5, 页码: 11
作者:  Wang, Yong-Cui;  Wang, Yong;  Yang, Zhi-Xia;  Deng, Nai-Yang
收藏  |  浏览/下载:149/0  |  提交时间:2018/07/30
Protein evolution in yeast transcription factor subnetworks 期刊论文
NUCLEIC ACIDS RESEARCH, 2010, 卷号: 38, 期号: 18, 页码: 5959-5969
作者:  Wang, Yong;  Franzosa, Eric A.;  Zhang, Xiang-Sun;  Xia, Yu
收藏  |  浏览/下载:148/0  |  提交时间:2018/07/30
SANA: an algorithm for sequential and non-sequential protein structure alignment 期刊论文
AMINO ACIDS, 2010, 卷号: 39, 期号: 2, 页码: 417-425
作者:  Wang, Lin;  Wu, Ling-Yun;  Wang, Yong;  Zhang, Xiang-Sun;  Chen, Luonan
收藏  |  浏览/下载:166/0  |  提交时间:2018/07/30
Protein structure alignment  Fold comparison  Circular permutation  Functional sites  
Prediction of protein-RNA binding sites by a random forest method with combined features 期刊论文
BIOINFORMATICS, 2010, 卷号: 26, 期号: 13, 页码: 1616-1622
作者:  Liu, Zhi-Ping;  Wu, Ling-Yun;  Wang, Yong;  Zhang, Xiang-Sun;  Chen, Luonan
收藏  |  浏览/下载:154/0  |  提交时间:2018/07/30
Computationally Probing Drug-Protein Interactions Via Support Vector Machine 期刊论文
LETTERS IN DRUG DESIGN & DISCOVERY, 2010, 卷号: 7, 期号: 5, 页码: 370-378
作者:  Wang, Yong-Cui;  Yang, Zhi-Xia;  Wang, Yong;  Deng, Nai-Yang
收藏  |  浏览/下载:129/0  |  提交时间:2018/07/30
Drug-target interaction  Chemical structure  Protein sequence  Imbalance problem  Support vector machine