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Circular Trajectory Reconstruction Uncovers Cell-Cycle Progression and Regulatory Dynamics from Single-Cell Hi-C Maps 期刊论文
ADVANCED SCIENCE, 2019, 页码: 13
作者:  Ye, Yusen;  Gao, Lin;  Zhang, Shihua
收藏  |  浏览/下载:295/0  |  提交时间:2020/01/10
cell cycle  chromosomal architectures  circular trajectory  dynamic structures  single-cell Hi-C maps  
A cluster-adjusted rank-based test for a clinical trial concerning multiple endpoints with application to dietary intervention assessment 期刊论文
BIOMETRICS, 2019, 卷号: 75, 期号: 3, 页码: 821-830
作者:  Zhang, Wei;  Liu, Aiyi;  Tang, Larry L.;  Li, Qizhai
收藏  |  浏览/下载:194/0  |  提交时间:2020/01/10
generalized Behrens-Fisher hypothesis  multivariate distributions  nonparametrics  rank statistics  type I errors  power of test  
Learning common and specific patterns from data of multiple interrelated biological scenarios with matrix factorization 期刊论文
NUCLEIC ACIDS RESEARCH, 2019, 卷号: 47, 期号: 13, 页码: 6606-6617
作者:  Zhang, Lihua;  Zhang, Shihua
收藏  |  浏览/下载:196/0  |  提交时间:2020/01/10
MSTD: an efficient method for detecting multi-scale topological domains from symmetric and asymmetric 3D genomic maps 期刊论文
NUCLEIC ACIDS RESEARCH, 2019, 卷号: 47, 期号: 11, 页码: 11
作者:  Ye, Yusen;  Gao, Lin;  Zhang, Shihua
收藏  |  浏览/下载:164/0  |  提交时间:2020/01/10
Simple tricks of convolutional neural network architectures improve DNA-protein binding prediction 期刊论文
BIOINFORMATICS, 2019, 卷号: 35, 期号: 11, 页码: 1837-1843
作者:  Cao, Zhen;  Zhang, Shihua
收藏  |  浏览/下载:193/0  |  提交时间:2020/01/10
The cis-trans binding strength defined by motif frequencies facilitates statistical inference of transcriptional regulation 期刊论文
BMC BIOINFORMATICS, 2019, 卷号: 20, 页码: 11
作者:  Feng, Yance;  Zhang, Sheng;  Li, Liang;  Li, Lei M.
收藏  |  浏览/下载:159/0  |  提交时间:2019/10/28
BASE  Statistical inference  Transcriptional regulation  PUFA  DHA  EPA  Binding strength  
PTMiner: Localization and Quality Control of Protein Modifications Detected in an Open Search and Its Application to Comprehensive Post-translational Modification Characterization in Human Proteome 期刊论文
MOLECULAR & CELLULAR PROTEOMICS, 2019, 卷号: 18, 期号: 2, 页码: 391-405
作者:  An, Zhiwu;  Zhai, Linhui;  Ying, Wantao;  Qian, Xiaohong;  Gong, Fuzhou;  Tan, Minjia;  Fu, Yan
收藏  |  浏览/下载:501/0  |  提交时间:2019/03/11
Improved matrix pooling 期刊论文
STATISTICAL METHODS IN MEDICAL RESEARCH, 2019, 卷号: 28, 期号: 1, 页码: 211-222
作者:  Xiong, Wenjun;  Ding, Juan;  He, Yuanzhen;  Li, Qizhai
收藏  |  浏览/下载:191/0  |  提交时间:2019/03/05
Matrix pooling  efficiency  group testing  sensitivity  specificity  
Discovering cooperative biomarkers for heterogeneous complex disease diagnoses 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2019, 卷号: 20, 期号: 1, 页码: 89-101
作者:  Sun, Duanchen;  Ren, Xianwen;  Ari, Eszter;  Korcsmaros, Tamas;  Csermely, Peter;  Wu, Ling-Yun
收藏  |  浏览/下载:305/0  |  提交时间:2019/03/05
heterogeneous diseases  cancer biomarker  network-based  cooperative biomarker  gene expression