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Reveal cell type-specific regulatory elements and their characterized histone code classes via a hidden Markov model 期刊论文
BMC GENOMICS, 2018, 卷号: 19, 页码: 13
作者:  Wang, Can;  Zhang, Shihua
收藏  |  浏览/下载：258/0  |  提交时间：2019/01/11
Epigenomics  Cell type-specific regulatory elements  Hidden Markov model  Histone modification  
Revealing transcription factor and histone modification co-localization and dynamics across cell lines by integrating ChIP-seq and RNA-seq data 期刊论文
BMC GENOMICS, 2018, 卷号: 19, 页码: 16
作者:  Zhang, Lirong;  Xue, Gaogao;  Liu, Junjie;  Li, Qianzhong;  Wang, Yong
收藏  |  浏览/下载：277/0  |  提交时间：2019/01/11
Transcription factor  Histone modification  Co-localization  Dynamics  
Integrative analysis of single-cell genomics data by coupled nonnegative matrix factorizations 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 卷号: 115, 期号: 30, 页码: 7723-7728
作者:  Duren, Zhana;  Chen, Xi;  Zamanighomi, Mahdi;  Zeng, Wanwen;  Satpathy, Ansuman T.;  Chang, Howard Y.;  Wang, Yong;  Wong, Wing Hung
收藏  |  浏览/下载：180/0  |  提交时间：2019/12/13
coupled clustering  NMF  single-cell genomic data  
Omics tools for the needle out of haystack? 期刊论文
JOURNAL OF GENETICS AND GENOMICS, 2018, 卷号: 45, 期号: 7, 页码: 343-344
作者:  Cao, Zhiwei;  Wang, Xiu-Jie;  Zhang, Shihua
收藏  |  浏览/下载：180/0  |  提交时间：2018/10/07
LPG: A four-group probabilistic approach to leveraging pleiotropy in genome-wide association studies 期刊论文
BMC Genomics, 2018, 卷号: 19, 期号: 1
作者:  Yang,Yi;  Dai,Mingwei;  Huang,Jian;  Lin,Xinyi;  Yang,Can;  Chen,Min;  Liu,Jin
收藏  |  浏览/下载：442/0  |  提交时间：2018/07/30
Pleiotropy  Variational Bayesian expectation-maximization  Genome-wide association studies  
Prediction of subcellular location of apoptosis proteins by incorporating PsePSSM and DCCA coefficient based on LFDA dimensionality reduction 期刊论文
BMC Genomics, 2018, 卷号: 19, 期号: 1
作者:  Yu,Bin;  Li,Shan;  Qiu,Wenying;  Wang,Minghui;  Du,Junwei;  Zhang,Yusen;  Chen,Xing
收藏  |  浏览/下载：181/0  |  提交时间：2018/07/30
Apoptosis proteins  Subcellular localization  Pseudo-position specific scoring matrix  Detrended cross-correlation analysis coefficient  Local fisher discriminant analysis  Support vector machine  
Matrix Integrative Analysis (MIA) of Multiple Genomic Data for Modular Patterns 期刊论文
FRONTIERS IN GENETICS, 2018, 卷号: 9, 页码: 12
作者:  Chen, Jinyu;  Zhang, Shihua
收藏  |  浏览/下载：182/0  |  提交时间：2018/07/30
bioinformatics  multi-dimensional genomics  matrix integrative analysis  data integration  module discovery  non-negative matrix factorization (NMF)  partial least squares (PLS)  
The Discovery of Mutated Driver Pathways in Cancer: Models and Algorithms 期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2018, 卷号: 15, 期号: 3, 页码: 988-998
作者:  Zhang, Junhua;  Zhang, Shihua
收藏  |  浏览/下载：218/0  |  提交时间：2018/07/30
Bioinformatics  cancer genomics  driver gene  driver pathway  mutual exclusivity  co-occurring mutation  
Reveal cell type-specific regulatory elements and their characterized histone code classes via a hidden Markov model 期刊论文
BMC GENOMICS, 2018, 卷号: 19
作者:  Wang, Can;  Zhang, Shihua
收藏  |  浏览/下载：152/0  |  提交时间：2019/04/03
Revealing transcription factor and histone modification co-localization and dynamics across cell lines by integrating ChIP-seq and RNA-seq data 期刊论文
BMC GENOMICS, 2018, 卷号: 19
作者:  Zhang, Lirong;  Xue, Gaogao;  Liu, Junjie;  Li, Qianzhong;  Wang, Yong
收藏  |  浏览/下载：230/0  |  提交时间：2019/04/03