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Disease category-specific annotation of variants using an ensemble learning framework 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2022, 卷号: 23, 期号: 1, 页码: 15
作者:  Cao, Zhen;  Huang, Yanting;  Duan, Ran;  Jin, Peng;  Qin, Zhaohui S.;  Zhang, Shihua
收藏  |  浏览/下载：122/0  |  提交时间：2022/06/21
complex disease  disease category  functional annotation  non-coding variant  ensemble learning  
Joint reconstruction of cis-regulatory interaction networks across multiple tissues using single-cell chromatin accessibility data 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2021, 卷号: 22, 期号: 3, 页码: 15
作者:  Dong, Kangning;  Zhang, Shihua
收藏  |  浏览/下载：115/0  |  提交时间：2022/04/02
cis-regulatory interaction networks  single-cell ATAC-seq  Gaussian graphical LASSO  
3D Genome of macaque fetal brain reveals evolutionary innovations during primate corticogenesis 期刊论文
CELL, 2021, 卷号: 184, 期号: 3, 页码: 723-+
作者:  Luo, Xin;  Liu, Yuting;  Dang, Dachang;  Hu, Ting;  Hou, Yingping;  Meng, Xiaoyu;  Zhang, Fengyun;  Li, Tingting;  Wang, Can;  Li, Min;  Wu, Haixu;  Shen, Qiushuo;  Hu, Yan;  Zeng, Xuerui;  He, Xiechao;  Yan, Lanzhen;  Zhang, Shihua;  Li, Cheng;  Su, Bing
收藏  |  浏览/下载：165/0  |  提交时间：2021/06/01
Prediction of enhancer-promoter interactions using the cross-cell type information and domain adversarial neural network 期刊论文
BMC BIOINFORMATICS, 2020, 卷号: 21, 期号: 1, 页码: 16
作者:  Jing, Fang;  Zhang, Shao-Wu;  Zhang, Shihua
收藏  |  浏览/下载：141/0  |  提交时间：2021/01/14
Enhancer–  promoter interactions  Cell line  Convolutional neural network  Transfer learning  Gradient reversal layer  
Prediction of enhancer–promoter interactions using the cross-cell type information and domain adversarial neural network 期刊论文
BMC Bioinformatics, 2020, 卷号: 21, 期号: 1
作者:  Jing,Fang;  Zhang,Shao-Wu;  Zhang,Shihua
收藏  |  浏览/下载：144/0  |  提交时间：2021/01/14
Enhancer–promoter interactions  Cell line  Convolutional neural network  Transfer learning  Gradient reversal layer  
Learning common and specific patterns from data of multiple interrelated biological scenarios with matrix factorization 期刊论文
NUCLEIC ACIDS RESEARCH, 2019, 卷号: 47, 期号: 13, 页码: 6606-6617
作者:  Zhang, Lihua;  Zhang, Shihua
收藏  |  浏览/下载：192/0  |  提交时间：2020/01/10
MSTD: an efficient method for detecting multi-scale topological domains from symmetric and asymmetric 3D genomic maps 期刊论文
NUCLEIC ACIDS RESEARCH, 2019, 卷号: 47, 期号: 11, 页码: 11
作者:  Ye, Yusen;  Gao, Lin;  Zhang, Shihua
收藏  |  浏览/下载：161/0  |  提交时间：2020/01/10
Model-based understanding of single-cell CRISPR screening 期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 11
作者:  Duan, Bin;  Zhou, Chi;  Zhu, Chengyu;  Yu, Yifei;  Li, Gaoyang;  Zhang, Shihua;  Zhang, Chao;  Ye, Xiangyun;  Ma, Hanhui;  Qu, Shen;  Zhang, Zhiyuan;  Wang, Ping;  Sun, Shuyang;  Liu, Qi
收藏  |  浏览/下载：191/0  |  提交时间：2020/01/10
Reveal cell type-specific regulatory elements and their characterized histone code classes via a hidden Markov model 期刊论文
BMC GENOMICS, 2018, 卷号: 19, 页码: 13
作者:  Wang, Can;  Zhang, Shihua
收藏  |  浏览/下载：251/0  |  提交时间：2019/01/11
Epigenomics  Cell type-specific regulatory elements  Hidden Markov model  Histone modification  
Sparse Weighted Canonical Correlation Analysis 期刊论文
CHINESE JOURNAL OF ELECTRONICS, 2018, 卷号: 27, 期号: 3, 页码: 459-466
作者:  Min Wenwen;  Liu Juan;  Zhang Shihua
收藏  |  浏览/下载：165/0  |  提交时间：2018/07/30
Canonical correlation analysis (CCA)  Sparse canonical correlation analysis (SCCA)  Sparse weighted CCA (SWCCA)  Group LASSO regularized SWCCA  Multi-view SWCCA