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Statistical test of structured continuous trees based on discordance matrix 期刊论文
BIOINFORMATICS, 2019, 卷号: 35, 期号: 23, 页码: 4962-4970
作者:  Bai, Xiangqi;  Ma, Liang;  Wan, Lin
收藏  |  浏览/下载：134/0  |  提交时间：2020/05/24
Associating lncRNAs with small molecules via bilevel optimization reveals cancer-related lncRNAs 期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2019, 卷号: 15, 期号: 12, 页码: 20
作者:  Wang, Yongcui;  Chen, Shilong;  Chen, Luonan;  Wang, Yong
收藏  |  浏览/下载：187/0  |  提交时间：2020/05/24
DC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data 期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 11
作者:  Zeng, Wanwen;  Chen, Xi;  Duren, Zhana;  Wang, Yong;  Jiang, Rui;  Wong, Wing Hung
收藏  |  浏览/下载：184/0  |  提交时间：2020/01/10
Hierarchical graphical model reveals HFR1 bridging circadian rhythm and flower development in Arabidopsis thaliana 期刊论文
NPJ SYSTEMS BIOLOGY AND APPLICATIONS, 2019, 卷号: 5, 页码: 11
作者:  Duren, Zhana;  Wang, Yaling;  Wang, Jiguang;  Zhao, Xing-Ming;  Lv, Le;  Li, Xiaobo;  Liu, Jingdong;  Zhu, Xin-Guang;  Chen, Luonan;  Wang, Yong
收藏  |  浏览/下载：174/0  |  提交时间：2020/05/24
Multi-scale analysis of schizophrenia risk genes, brain structure, and clinical symptoms reveals integrative clues for subtyping schizophrenia patients 期刊论文
JOURNAL OF MOLECULAR CELL BIOLOGY, 2019, 卷号: 11, 期号: 8, 页码: 678-687
作者:  Ma, Liang;  Rolls, Edmund T.;  Liu, Xiuqin;  Liu, Yuting;  Jiao, Zeyu;  Wang, Yue;  Gong, Weikang;  Ma, Zhiming;  Gong, Fuzhou;  Wan, Lin
收藏  |  浏览/下载：229/0  |  提交时间：2020/05/24
Schizophrenia  PANSS  multi-scale analysis  hot cluster  grey matter volume  pathway  
The cis-trans binding strength defined by motif frequencies facilitates statistical inference of transcriptional regulation 期刊论文
BMC BIOINFORMATICS, 2019, 卷号: 20, 页码: 11
作者:  Feng, Yance;  Zhang, Sheng;  Li, Liang;  Li, Lei M.
收藏  |  浏览/下载：157/0  |  提交时间：2019/10/28
BASE  Statistical inference  Transcriptional regulation  PUFA  DHA  EPA  Binding strength  
TSEE: an elastic embedding method to visualize the dynamic gene expression patterns of time series single-cell RNA sequencing data 期刊论文
BMC GENOMICS, 2019, 卷号: 20, 页码: 16
作者:  An, Shaokun;  Ma, Liang;  Wan, Lin
收藏  |  浏览/下载：202/0  |  提交时间：2019/10/28
Nonlinear dimensionality reduction  Elastic embedding  Visualization  Single-cell RNA sequencing  Time series  Cell fate decisions  Gene expression pattern  Oscillation  In-group proportion  
Parameter Estimation and Variable Selection for Big Systems of Linear Ordinary Differential Equations: A Matrix-Based Approach 期刊论文
JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION, 2019, 卷号: 114, 期号: 526, 页码: 657-667
作者:  Wu, Leqin;  Qiu, Xing;  Yuan, Ya-xiang;  Wu, Hulin
收藏  |  浏览/下载：187/0  |  提交时间：2020/01/10
Complex system  Eigenvalue updating algorithm  High dimension  Matrix-based variable selection  Ordinary differential equation  Separable least squares  
Multi-Level Comparative Framework Based on Gene Pair-Wise Expression Across Three Insulin Target Tissues for Type 2 Diabetes 期刊论文
FRONTIERS IN GENETICS, 2019, 卷号: 10, 页码: 16
作者:  Sun, Shaoyan;  Sung, Fengnan;  Wang, Yong
收藏  |  浏览/下载：199/0  |  提交时间：2020/01/10
type 2 diabetes  gene pairwise expression  dysfunctional interactions  multi-level analysis  random walk with restart  
TFAP2C-and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment 期刊论文
CELL STEM CELL, 2019, 卷号: 24, 期号: 2, 页码: 271-+
作者:  Li, Lingjie;  Wang, Yong;  Torkelson, Jessica L.;  Shankar, Gautam;  Pattison, Jillian M.;  Zhen, Hanson H.;  Fang, Fengqin;  Duren, Zhana;  Xin, Jingxue;  Gaddam, Sadhana;  Melo, Sandra P.;  Piekos, Samantha N.;  Li, Jiang;  Liaw, Eric J.;  Chen, Lang;  Li, Rui;  Wernig, Marius;  Wong, Wing H.;  Chang, Howard Y.;  Oro, Anthony E.
收藏  |  浏览/下载：288/0  |  提交时间：2019/03/11