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Annotating regulatory elements by heterogeneous network embedding 期刊论文
BIOINFORMATICS, 2022, 页码: 13
作者:  Lu, Yurun;  Feng, Zhanying;  Zhang, Songmao;  Wang, Yong
收藏  |  浏览/下载:139/0  |  提交时间:2022/06/21
MIMIC: an optimization method to identify cell type-specific marker panel for cell sorting 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2021, 卷号: 22, 期号: 6, 页码: 14
作者:  Zou, Meng;  Duren, Zhana;  Yuan, Qiuyue;  Li, Henry;  Hutchins, Andrew Paul;  Wong, Wing Hung;  Wang, Yong
收藏  |  浏览/下载:146/0  |  提交时间:2022/04/02
cell type-specific marker  TFs  surface markers  dimension reduction  hierarchical topology  
Approximate distance correlation for selecting highly interrelated genes across datasets 期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2021, 卷号: 17, 期号: 11, 页码: 18
作者:  Shen, Qunlun;  Zhang, Shihua
收藏  |  浏览/下载:117/0  |  提交时间:2022/04/02
Imputing single-cell RNA-seq data by considering cell heterogeneity and prior expression of dropouts 期刊论文
JOURNAL OF MOLECULAR CELL BIOLOGY, 2021, 卷号: 13, 期号: 1, 页码: 29-40
作者:  Zhang, Lihua;  Zhang, Shihua
收藏  |  浏览/下载:131/0  |  提交时间:2021/10/26
single-cell RNA-seq  dropout  imputation  low-rank  systems biology  
Comparison of Computational Methods for Imputing Single-Cell RNA-Sequencing Data 期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2020, 卷号: 17, 期号: 2, 页码: 376-389
作者:  Zhang, Lihua;  Zhang, Shihua
收藏  |  浏览/下载:164/0  |  提交时间:2020/05/24
Gene expression  Sequential analysis  Bioinformatics  RNA  Matrix converters  Computational biology  Bayes methods  Single-cell RNA-sequencing technique  dropout event  imputation  algorithm  bioinformatics  
ELF: Extract Landmark Features By Optimizing Topology Maintenance, Redundancy, and Specificity 期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2020, 卷号: 17, 期号: 2, 页码: 411-421
作者:  Feng, Zhan-Ying;  Wang, Yong
收藏  |  浏览/下载:186/0  |  提交时间:2020/05/24
Feature extraction  Topology  Ground penetrating radar  Geophysical measurement techniques  Redundancy  Maintenance engineering  Manganese  Feature selection  topology maintenance  optimization  single cell  
Learning common and specific patterns from data of multiple interrelated biological scenarios with matrix factorization 期刊论文
NUCLEIC ACIDS RESEARCH, 2019, 卷号: 47, 期号: 13, 页码: 6606-6617
作者:  Zhang, Lihua;  Zhang, Shihua
收藏  |  浏览/下载:192/0  |  提交时间:2020/01/10
MSIQ: JOINT MODELING OF MULTIPLE RNA-SEQ SAMPLES FOR ACCURATE ISOFORM QUANTIFICATION 期刊论文
ANNALS OF APPLIED STATISTICS, 2018, 卷号: 12, 期号: 1, 页码: 510-539
作者:  Li, Wei Vivian;  Zhao, Anqi;  Zhang, Shihua;  Li, Jingyi Jessica
收藏  |  浏览/下载:195/0  |  提交时间:2018/07/30
Isoform abundance estimation  joint inference from multiple samples  RNA sequencing  Bayesian hierarchical models  Gibbs sampling  data heterogeneity