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Deciphering the Spatial Modular Patterns of Tissues by Integrating Spatial and Single-Cell Transcriptomic Data 期刊论文
JOURNAL OF COMPUTATIONAL BIOLOGY, 2022, 页码: 14
作者:  Shan, Xu;  Chen, Jinyu;  Dong, Kangning;  Zhou, Wei;  Zhang, Shihua
收藏  |  浏览/下载：74/0  |  提交时间：2023/02/07
data integration  single-cell transcriptomics  spatial modular patterns  spatial transcriptomics  
hDirect-MAP: projection-free single-cell modeling of response to checkpoint immunotherapy 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2022, 卷号: 23, 期号: 2, 页码: 16
作者:  Lu, Yong;  Xue, Gang;  Zheng, Ningbo;  Han, Kun;  Yang, Wenzhong;  Wang, Rui-Sheng;  Wu, Lingyun;  Miller, Lance D.;  Pardee, Timothy;  Triozzi, Pierre L.;  Lo, Hui-Wen;  Watabe, Kounosuke;  Wong, Stephen T. C.;  Pasche, Boris C.;  Zhang, Wei;  Jin, Guangxu
收藏  |  浏览/下载：118/0  |  提交时间：2023/02/07
single-cell RNA sequencing (scRNA-seq)  single-cell mass cytometry (CyTOF)  Pareto optimization  projection-free single-cell modeling  response to immune checkpoint blockade  
Identifying phenotype-associated subpopulations by integrating bulk and single-cell sequencing data 期刊论文
NATURE BIOTECHNOLOGY, 2021, 页码: 18
作者:  Sun, Duanchen;  Guan, Xiangnan;  Moran, Amy E.;  Wu, Ling-Yun;  Qian, David Z.;  Schedin, Pepper;  Dai, Mu-Shui;  Danilov, Alexey, V;  Alumkal, Joshi J.;  Adey, Andrew C.;  Spellman, Paul T.;  Xia, Zheng
收藏  |  浏览/下载：138/0  |  提交时间：2022/04/02
MIMIC: an optimization method to identify cell type-specific marker panel for cell sorting 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2021, 卷号: 22, 期号: 6, 页码: 14
作者:  Zou, Meng;  Duren, Zhana;  Yuan, Qiuyue;  Li, Henry;  Hutchins, Andrew Paul;  Wong, Wing Hung;  Wang, Yong
收藏  |  浏览/下载：135/0  |  提交时间：2022/04/02
cell type-specific marker  TFs  surface markers  dimension reduction  hierarchical topology  
Approximate distance correlation for selecting highly interrelated genes across datasets 期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2021, 卷号: 17, 期号: 11, 页码: 18
作者:  Shen, Qunlun;  Zhang, Shihua
收藏  |  浏览/下载：114/0  |  提交时间：2022/04/02
MUREN: a robust and multi-reference approach of RNA-seq transcript normalization 期刊论文
BMC Bioinformatics, 2021, 卷号: 22, 期号: 1
作者:  Feng,Yance;  Li,Lei M.
收藏  |  浏览/下载：124/0  |  提交时间：2021/10/26
RNA-seq  Normalization  Asymmetrically regulated transcription profiles (ART)  Skewness  Mode  Multi-reference  
A kernel non-negative matrix factorization framework for single cell clustering 期刊论文
APPLIED MATHEMATICAL MODELLING, 2021, 卷号: 90, 页码: 875-888
作者:  Jiang, Hao;  Yi, Ming;  Zhang, Shihua
收藏  |  浏览/下载：124/0  |  提交时间：2021/04/26
Single cell RNA-sequencing  Kernel non-negative matrix factorization  Cellular heterogeneity  
Imputing single-cell RNA-seq data by considering cell heterogeneity and prior expression of dropouts 期刊论文
JOURNAL OF MOLECULAR CELL BIOLOGY, 2021, 卷号: 13, 期号: 1, 页码: 29-40
作者:  Zhang, Lihua;  Zhang, Shihua
收藏  |  浏览/下载：125/0  |  提交时间：2021/10/26
single-cell RNA-seq  dropout  imputation  low-rank  systems biology  
NeuralEE: A GPU-Accelerated Elastic Embedding Dimensionality Reduction Method for Visualizing Large-Scale scRNA-Seq Data 期刊论文
FRONTIERS IN GENETICS, 2020, 卷号: 11, 页码: 8
作者:  Xiong, Jiankang;  Gong, Fuzhou;  Wan, Lin;  Ma, Liang
收藏  |  浏览/下载：164/0  |  提交时间：2021/01/14
single-cell RNA sequencing  elastic embedding  neural networks  large-scale  stochastic optimization  parametric models  generalizable models  
scTIM: seeking cell-type-indicative marker from single cell RNA-seq data by consensus optimization 期刊论文
BIOINFORMATICS, 2020, 卷号: 36, 期号: 8, 页码: 2474-2485
作者:  Feng, Zhanying;  Ren, Xianwen;  Fang, Yuan;  Yin, Yining;  Huang, Chutian;  Zhao, Yimin;  Wang, Yong
收藏  |  浏览/下载：178/0  |  提交时间：2020/06/30