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Network diffusion for scalable embedding of massive single-cell ATAC-seq data 期刊论文
SCIENCE BULLETIN, 2021, 卷号: 66, 期号: 22, 页码: 2271-2276
作者:  Dong, Kangning;  Zhang, Shihua
收藏  |  浏览/下载:116/0  |  提交时间:2022/04/02
Joint reconstruction of cis-regulatory interaction networks across multiple tissues using single-cell chromatin accessibility data 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2021, 卷号: 22, 期号: 3, 页码: 15
作者:  Dong, Kangning;  Zhang, Shihua
收藏  |  浏览/下载:115/0  |  提交时间:2022/04/02
cis-regulatory interaction networks  single-cell ATAC-seq  Gaussian graphical LASSO  
Imputing single-cell RNA-seq data by considering cell heterogeneity and prior expression of dropouts 期刊论文
JOURNAL OF MOLECULAR CELL BIOLOGY, 2021, 卷号: 13, 期号: 1, 页码: 29-40
作者:  Zhang, Lihua;  Zhang, Shihua
收藏  |  浏览/下载:131/0  |  提交时间:2021/10/26
single-cell RNA-seq  dropout  imputation  low-rank  systems biology