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Models of global gene expression define major domains of cell type and tissue identity 期刊论文
NUCLEIC ACIDS RESEARCH, 2017, 卷号: 45, 期号: 5, 页码: 2354-2367
作者:  Hutchins, Andrew P.;  Yang, Zhongzhou;  Li, Yuhao;  He, Fangfang;  Fu, Xiuling;  Wang, Xiaoshan;  Li, Dongwei;  Liu, Kairong;  He, Jiangping;  Wang, Yong;  Chen, Jiekai;  Esteban, Miguel A.;  Pei, Duanqing
收藏  |  浏览/下载：197/0  |  提交时间：2018/07/30
Modeling the causal regulatory network by integrating chromatin accessibility and transcriptome data 期刊论文
NATIONAL SCIENCE REVIEW, 2016, 卷号: 3, 期号: 2, 页码: 240-251
作者:  Wang, Yong;  Jiang, Rui;  Wong, Wing Hung
收藏  |  浏览/下载：149/0  |  提交时间：2018/07/30
gene regulatory network  open chromatin  DNA accessibility  transcription factor colocalization  statistical model  data integration  
Identifying joint biomarker panel from multiple level dataset by an optimization model 期刊论文
BIOMARKERS IN MEDICINE, 2016, 卷号: 10, 期号: 6, 页码: 567-575
作者:  Zou, Meng;  Zhang, Peng-Jun;  Chen, Luonan;  Tian, Ya-Ping;  Wang, Yong
收藏  |  浏览/下载：170/0  |  提交时间：2018/07/30
group lasso optimization  joint biomarker panel  multiple level dataset  
A systematic method to identify modulation of transcriptional regulation via chromatin activity reveals regulatory network during mESC differentiation 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6, 页码: 12
作者:  Duren, Zhana;  Wang, Yong
收藏  |  浏览/下载：173/0  |  提交时间：2018/07/30
A novel mixed integer programming for multi-biomarker panel identification by distinguishing malignant from benign colorectal tumors 期刊论文
METHODS, 2015, 卷号: 83, 页码: 3-17
作者:  Zou, Meng;  Zhang, Peng-Jun;  Wen, Xin-Yu;  Chen, Luonan;  Tian, Ya-Ping;  Wang, Yong
收藏  |  浏览/下载：170/0  |  提交时间：2018/07/30
Translational bioinformatics  Multi-biomarker  Colorectal cancer  Mixed integer programming