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Integrated profiling of human pancreatic cancer organoids reveals chromatin accessibility features associated with drug sensitivity 期刊论文
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 16
作者:  Shi, Xiaohan;  Li, Yunguang;  Yuan, Qiuyue;  Tang, Shijie;  Guo, Shiwei;  Zhang, Yehan;  He, Juan;  Zhang, Xiaoyu;  Han, Ming;  Liu, Zhuang;  Zhu, Yiqin;  Gao, Suizhi;  Wang, Huan;  Xu, Xiongfei;  Zheng, Kailian;  Jing, Wei;  Chen, Luonan;  Wang, Yong;  Jin, Gang;  Gao, Dong
收藏  |  浏览/下载：141/0  |  提交时间：2022/06/21
Annotating regulatory elements by heterogeneous network embedding 期刊论文
BIOINFORMATICS, 2022, 页码: 13
作者:  Lu, Yurun;  Feng, Zhanying;  Zhang, Songmao;  Wang, Yong
收藏  |  浏览/下载：157/0  |  提交时间：2022/06/21
MIMIC: an optimization method to identify cell type-specific marker panel for cell sorting 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2021, 卷号: 22, 期号: 6, 页码: 14
作者:  Zou, Meng;  Duren, Zhana;  Yuan, Qiuyue;  Li, Henry;  Hutchins, Andrew Paul;  Wong, Wing Hung;  Wang, Yong
收藏  |  浏览/下载：164/0  |  提交时间：2022/04/02
cell type-specific marker  TFs  surface markers  dimension reduction  hierarchical topology  
Reusability report: Compressing regulatory networks to vectors for interpreting gene expression and genetic variants 期刊论文
NATURE MACHINE INTELLIGENCE, 2021, 卷号: 3, 期号: 7, 页码: 576-580
作者:  Zeng, Wanwen;  Xin, Jingxue;  Jiang, Rui;  Wang, Yong
收藏  |  浏览/下载：128/0  |  提交时间：2021/10/26
ELF: Extract Landmark Features By Optimizing Topology Maintenance, Redundancy, and Specificity 期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2020, 卷号: 17, 期号: 2, 页码: 411-421
作者:  Feng, Zhan-Ying;  Wang, Yong
收藏  |  浏览/下载：209/0  |  提交时间：2020/05/24
Feature extraction  Topology  Ground penetrating radar  Geophysical measurement techniques  Redundancy  Maintenance engineering  Manganese  Feature selection  topology maintenance  optimization  single cell  
Associating lncRNAs with small molecules via bilevel optimization reveals cancer-related lncRNAs 期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2019, 卷号: 15, 期号: 12, 页码: 20
作者:  Wang, Yongcui;  Chen, Shilong;  Chen, Luonan;  Wang, Yong
收藏  |  浏览/下载：195/0  |  提交时间：2020/05/24
TFAP2C-and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment 期刊论文
CELL STEM CELL, 2019, 卷号: 24, 期号: 2, 页码: 271-+
作者:  Li, Lingjie;  Wang, Yong;  Torkelson, Jessica L.;  Shankar, Gautam;  Pattison, Jillian M.;  Zhen, Hanson H.;  Fang, Fengqin;  Duren, Zhana;  Xin, Jingxue;  Gaddam, Sadhana;  Melo, Sandra P.;  Piekos, Samantha N.;  Li, Jiang;  Liaw, Eric J.;  Chen, Lang;  Li, Rui;  Wernig, Marius;  Wong, Wing H.;  Chang, Howard Y.;  Oro, Anthony E.
收藏  |  浏览/下载：310/0  |  提交时间：2019/03/11
A Semisupervised Classification Approach for Multidomain Networks With Domain Selection 期刊论文
IEEE TRANSACTIONS ON NEURAL NETWORKS AND LEARNING SYSTEMS, 2019, 卷号: 30, 期号: 1, 页码: 269-283
作者:  Chen, Chuan;  Xin, Jingxue;  Wang, Yong;  Chen, Luonan;  Ng, Michael K.
收藏  |  浏览/下载：269/0  |  提交时间：2019/03/05
Domain selection  multidomain classification  network integration  semisupervised learning  sparsity  
Modeling gene regulation from paired expression and chromatin accessibility data 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, 卷号: 114, 期号: 25, 页码: E4914-E4923
作者:  Duren, Zhana;  Chen, Xi;  Jiang, Rui;  Wang, Yong;  Wong, Wing Hung
收藏  |  浏览/下载：174/0  |  提交时间：2018/07/30
gene regulation  transcription factor  regulatory element  chromatin regulator  chromatin activity