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Recognition of Structure Similarities in Proteins
Wang, Lin1; Qiu, Yuqing; Wang, Jiguang; Zhang, Xiangsun1
AbstractProtein fold structure is more conserved than its amino acid sequence and closely associated with biological function, so calculating the similarity of protein structures is a fundamental problem in structural biology and plays a key role in protein fold classification, fold function inference, and protein structure prediction. Large progress has been made in recent years in this field and many methods for considering structural similarity have been proposed, including methods for protein structure comparison, retrieval of protein structures from databases, and ligand binding site comparison. Most of those methods can be available on the World Wide Web, but evaluation of all the methods is still a hard problem. This paper summarizes some popular methods and latest methods for structure similarities, including structure alignment, protein structure retrieval, and ligand binding site alignment.
KeywordBinding site alignment circular permutations flexible alignment protein structure alignment protein structure retrieval
Funding ProjectNational Natural Science Foundation of China under Key Research[10631070] ; JSPs ; JSPS-NSFC[10711140116]
WOS Research AreaMathematics
WOS SubjectMathematics, Interdisciplinary Applications
WOS IDWOS:000260878200014
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Document Type期刊论文
Corresponding AuthorWang, Lin
Affiliation1.Chinese Acad Sci, Acad Math & Syst Sci, Beijing 100190, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
Recommended Citation
GB/T 7714
Wang, Lin,Qiu, Yuqing,Wang, Jiguang,et al. Recognition of Structure Similarities in Proteins[J]. JOURNAL OF SYSTEMS SCIENCE & COMPLEXITY,2008,21(4):665-675.
APA Wang, Lin,Qiu, Yuqing,Wang, Jiguang,&Zhang, Xiangsun.(2008).Recognition of Structure Similarities in Proteins.JOURNAL OF SYSTEMS SCIENCE & COMPLEXITY,21(4),665-675.
MLA Wang, Lin,et al."Recognition of Structure Similarities in Proteins".JOURNAL OF SYSTEMS SCIENCE & COMPLEXITY 21.4(2008):665-675.
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