KMS Of Academy of mathematics and systems sciences, CAS
| Nonparametric estimation of distributions and diagnostic accuracy based on group-tested results with differential misclassification | |
Zhang, Wei1 ; Liu, Aiyi2; Li, Qizhai1; Albert, Paul S.3
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| 2020-03-05 | |
| Source Publication | BIOMETRICS
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| ISSN | 0006-341X |
| Pages | 10 |
| Abstract | This article concerns the problem of estimating a continuous distribution in a diseased or nondiseased population when only group-based test results on the disease status are available. The problem is challenging in that individual disease statuses are not observed and testing results are often subject to misclassification, with further complication that the misclassification may be differential as the group size and the number of the diseased individuals in the group vary. We propose a method to construct nonparametric estimation of the distribution and obtain its asymptotic properties. The performance of the distribution estimator is evaluated under various design considerations concerning group sizes and classification errors. The method is exemplified with data from the National Health and Nutrition Examination Survey study to estimate the distribution and diagnostic accuracy of C-reactive protein in blood samples in predicting chlamydia incidence. |
| Keyword | coverage probability diagnostic accuracy differential misclassification group testing integrated absolute bias integrated mean squared error rare disease ROC curves |
| DOI | 10.1111/biom.13236 |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | Intramural Research Program of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) ; Beijing Natural Science Foundation[Z180006] ; National Nature Science Foundation of China[11722113] ; Intramural Research Program of theNational Cancer Institute (NCI) |
| WOS Research Area | Life Sciences & Biomedicine - Other Topics ; Mathematical & Computational Biology ; Mathematics |
| WOS Subject | Biology ; Mathematical & Computational Biology ; Statistics & Probability |
| WOS ID | WOS:000560958200001 |
| Publisher | WILEY |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.amss.ac.cn/handle/2S8OKBNM/52040 |
| Collection | 系统科学研究所 |
| Corresponding Author | Liu, Aiyi |
| Affiliation | 1.Chinese Acad Sci, Acad Math & Syst Sci, NCMIS, LSC, Beijing, Peoples R China 2.Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Biostat & Bioinformat Branch, NIH, Bethesda, MD 20892 USA 3.NCI, Biostat Branch, Div Canc Epidemiol & Genet, NIH, Bethesda, MD 20892 USA |
| Recommended Citation GB/T 7714 | Zhang, Wei,Liu, Aiyi,Li, Qizhai,et al. Nonparametric estimation of distributions and diagnostic accuracy based on group-tested results with differential misclassification[J]. BIOMETRICS,2020:10. |
| APA | Zhang, Wei,Liu, Aiyi,Li, Qizhai,&Albert, Paul S..(2020).Nonparametric estimation of distributions and diagnostic accuracy based on group-tested results with differential misclassification.BIOMETRICS,10. |
| MLA | Zhang, Wei,et al."Nonparametric estimation of distributions and diagnostic accuracy based on group-tested results with differential misclassification".BIOMETRICS (2020):10. |
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