A new geometric-topological method to measure protein fold similarity

doi:10.1016/j.cplett.2006.11.071

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	A new geometric-topological method to measure protein fold similarity
	Wu, Zikai ; Wang, Yong; Feng, Enmin ; Chen, Luonan
	2007-01-12
发表期刊	CHEMICAL PHYSICS LETTERS
ISSN	0009-2614
卷号	433 期号:4-6 页码:432-438
摘要	In this Letter, a novel hybrid representation of protein structure is proposed by utilizing two sources of information. One is the distribution of C(alpha)-C(alpha) distances with sequence separation three, which describes the local geometry property and is used to identify contents of regular secondary structures; the other is the linear sequence distance distribution of medium and long range interactions, which represents packing arrangement and topological connections between secondary structures. Furthermore, we introduce a new protein structure comparison method based on information theory. Cluster analysis and structure classification experiments on several data sets demonstrate its effectiveness on measuring protein fold similarity. (c) 2006 Elsevier B.V. All rights reserved.
DOI	10.1016/j.cplett.2006.11.071
语种	英语
WOS研究方向	Chemistry ; Physics
WOS类目	Chemistry, Physical ; Physics, Atomic, Molecular & Chemical
WOS记录号	WOS:000243900700034
出版者	ELSEVIER SCIENCE BV
引用统计
文献类型	期刊论文
条目标识符	http://ir.amss.ac.cn/handle/2S8OKBNM/5126
专题	应用数学研究所
通讯作者	Wu, Zikai
作者单位	1.Dalian Univ Technol, Dept Appl Math, Dalian 116024, Peoples R China 2.Chinese Acad Sci, Acad Math & Syst Sci, Inst Appl Math, Beijing 100080, Peoples R China 3.Osaka Sangyo Univ, Dept Elect Informat & Commun, Osaka 5748530, Japan 4.Shanghai Univ, Inst Syst Biol, Shanghai 200444, Peoples R China
推荐引用方式 GB/T 7714	Wu, Zikai,Wang, Yong,Feng, Enmin,et al. A new geometric-topological method to measure protein fold similarity[J]. CHEMICAL PHYSICS LETTERS,2007,433(4-6):432-438.
APA	Wu, Zikai,Wang, Yong,Feng, Enmin,&Chen, Luonan.(2007).A new geometric-topological method to measure protein fold similarity.CHEMICAL PHYSICS LETTERS,433(4-6),432-438.
MLA	Wu, Zikai,et al."A new geometric-topological method to measure protein fold similarity".CHEMICAL PHYSICS LETTERS 433.4-6(2007):432-438.