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The Cox-Aalen model for recurrent-event data with a dependent terminal event
Qu, Lianqiang1; Sun, Liuquan2
2019-05-01
Source PublicationSTATISTICA NEERLANDICA
ISSN0039-0402
Volume73Issue:2Pages:234-255
AbstractRecurrent events with a dependent terminal event arise frequently in a wide variety of fields. In this paper, we propose a new joint model to analyze these data and model the dependence between recurrent and terminal events through shared gamma frailty. Specifically, a Cox-Aalen rate frailty model is specified for the recurrent event, and an additive hazards frailty model is specified for the terminal event. An estimating equation approach is developed for the parameters in the joint model, and the asymptotic properties of the proposed estimators are established. Simulation studies demonstrate that the proposed estimators perform well with finite samples. An application to a medical cost study of chronic heart failure patients is illustrated.
KeywordCox-Aalen model estimating equation recurrent events share frailty terminal event
DOI10.1111/stan.12167
Language英语
Funding ProjectNational Natural Science Foundation of China[11771431] ; National Natural Science Foundation of China[11690015] ; Key Laboratory of Random Complex Structures and Data Science, Chinese Academy of Sciences[2008DP173182] ; Fundamental Research Funds for the Central Universities[20205180090]
WOS Research AreaMathematics
WOS SubjectStatistics & Probability
WOS IDWOS:000466377800006
PublisherWILEY
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Document Type期刊论文
Identifierhttp://ir.amss.ac.cn/handle/2S8OKBNM/34605
Collection应用数学研究所
Corresponding AuthorSun, Liuquan
Affiliation1.Cent China Normal Univ, Sch Math & Stat, Wuhan 430079, Hubei, Peoples R China
2.Chinese Acad Sci, Acad Math & Syst Sci, Inst Appl Math, Beijing 100190, Peoples R China
Recommended Citation
GB/T 7714
Qu, Lianqiang,Sun, Liuquan. The Cox-Aalen model for recurrent-event data with a dependent terminal event[J]. STATISTICA NEERLANDICA,2019,73(2):234-255.
APA Qu, Lianqiang,&Sun, Liuquan.(2019).The Cox-Aalen model for recurrent-event data with a dependent terminal event.STATISTICA NEERLANDICA,73(2),234-255.
MLA Qu, Lianqiang,et al."The Cox-Aalen model for recurrent-event data with a dependent terminal event".STATISTICA NEERLANDICA 73.2(2019):234-255.
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