The Cox-Aalen model for recurrent-event data with a dependent terminal event

doi:10.1111/stan.12167

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	The Cox-Aalen model for recurrent-event data with a dependent terminal event
	Qu, Lianqiang 1; Sun, Liuquan2
	2019-05-01
发表期刊	STATISTICA NEERLANDICA
ISSN	0039-0402
卷号	73 期号:2 页码:234-255
摘要	Recurrent events with a dependent terminal event arise frequently in a wide variety of fields. In this paper, we propose a new joint model to analyze these data and model the dependence between recurrent and terminal events through shared gamma frailty. Specifically, a Cox-Aalen rate frailty model is specified for the recurrent event, and an additive hazards frailty model is specified for the terminal event. An estimating equation approach is developed for the parameters in the joint model, and the asymptotic properties of the proposed estimators are established. Simulation studies demonstrate that the proposed estimators perform well with finite samples. An application to a medical cost study of chronic heart failure patients is illustrated.
关键词	Cox-Aalen model estimating equation recurrent events share frailty terminal event
DOI	10.1111/stan.12167
语种	英语
资助项目	National Natural Science Foundation of China[11771431] ; National Natural Science Foundation of China[11690015] ; Key Laboratory of Random Complex Structures and Data Science, Chinese Academy of Sciences[2008DP173182] ; Fundamental Research Funds for the Central Universities[20205180090]
WOS研究方向	Mathematics
WOS类目	Statistics & Probability
WOS记录号	WOS:000466377800006
出版者	WILEY
引用统计
文献类型	期刊论文
条目标识符	http://ir.amss.ac.cn/handle/2S8OKBNM/34605
专题	应用数学研究所
通讯作者	Sun, Liuquan
作者单位	1.Cent China Normal Univ, Sch Math & Stat, Wuhan 430079, Hubei, Peoples R China 2.Chinese Acad Sci, Acad Math & Syst Sci, Inst Appl Math, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Qu, Lianqiang,Sun, Liuquan. The Cox-Aalen model for recurrent-event data with a dependent terminal event[J]. STATISTICA NEERLANDICA,2019,73(2):234-255.
APA	Qu, Lianqiang,&Sun, Liuquan.(2019).The Cox-Aalen model for recurrent-event data with a dependent terminal event.STATISTICA NEERLANDICA,73(2),234-255.
MLA	Qu, Lianqiang,et al."The Cox-Aalen model for recurrent-event data with a dependent terminal event".STATISTICA NEERLANDICA 73.2(2019):234-255.