CSpace  > 系统科学研究所
Principles of Inter-Amino-Acid Recognition Revealed by Binding Energies between Homogeneous Oligopeptides
Du, Huiwen1,2,8; Hu, Xiaoyu3; Duan, Hongyang1,2,8; Yu, Lanlan1,2,8; Qu, Fuyang1,2,8; Huang, Qunxing1,2,8; Zheng, Wangshu1,2,8; Xie, Hanyi1,2,8; Peng, Jiaxi1,2,8; Tuo, Rui4; Yu, Dan4; Lin, Yuchen1,2,8; Li, Wenzhe1,2,8; Zheng, Yongfang1,2,8; Fang, Xiaocui1,2,8; Zou, Yimin1,2,8; Wang, Huayi1,2,8; Wang, Mengting1,2,8; Weiss, Paul S.5,6; Yang, Yanlian1,2,8; Wang, Chen1,2,7,8
2019-01-23
Source PublicationACS CENTRAL SCIENCE
ISSN2374-7943
Volume5Issue:1Pages:97-108
AbstractWe have determined the interaction strengths of the common naturally occurring amino acids using a complete binding affinity matrix of 20 x 20 pairs of homo-octapeptides consisting of the 20 common amino acids between stationary and mobile states. We used a bead-based fluorescence assay for these measurements. The results provide a basis for analyzing specificity, polymorphisms, and selectivity of inter-amino-acid interactions. Comparative analyses of the binding energies, i.e., the free energies of association (Delta G(A)), reveal contributions assignable to both main-chain-related and side-chain-related interactions originating from the chemical structures of these 20 common amino acids. Side-chain-side-chain and side-chain-main-chain interactions are found to be pronounced in an identified set of amino acid pairs that determine the basis of inter-amino-acid recognition.
DOI10.1021/acscentsci.8b00723
Language英语
Funding ProjectNational Natural Science Foundation of China[21673055] ; National Natural Science Foundation of China[21721002] ; National Natural Science Foundation of China[21773042] ; Key Research Program of Frontier Sciences, CAS[QYZDJ-SSW-SLH048] ; National Key Research and Development Program of China[2016YFF0203803]
WOS Research AreaChemistry
WOS SubjectChemistry, Multidisciplinary
WOS IDWOS:000456525100012
PublisherAMER CHEMICAL SOC
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.amss.ac.cn/handle/2S8OKBNM/32181
Collection系统科学研究所
Affiliation1.Chinese Acad Sci, Key Lab Biomed Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China
2.Chinese Acad Sci, Natl Ctr Nanosci & Technol, Key Lab Standardizat & Measurement Nanotechnol, Beijing 100190, Peoples R China
3.Univ Chinese Acad Sci, Coll Math Sci, Beijing 100049, Peoples R China
4.Chinese Acad Sci, Acad Math & Syst Sci, Beijing 100190, Peoples R China
5.Univ Calif Los Angeles, Dept Chem & Biochem, Calif NanoSyst Inst, Los Angeles, CA 90095 USA
6.Univ Calif Los Angeles, Dept Mat Sci & Engn, Los Angeles, CA 90095 USA
7.Chinese Acad Sci, CAS Ctr Excellence Brain Sci, Beijing 100101, Peoples R China
8.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
Recommended Citation
GB/T 7714
Du, Huiwen,Hu, Xiaoyu,Duan, Hongyang,et al. Principles of Inter-Amino-Acid Recognition Revealed by Binding Energies between Homogeneous Oligopeptides[J]. ACS CENTRAL SCIENCE,2019,5(1):97-108.
APA Du, Huiwen.,Hu, Xiaoyu.,Duan, Hongyang.,Yu, Lanlan.,Qu, Fuyang.,...&Wang, Chen.(2019).Principles of Inter-Amino-Acid Recognition Revealed by Binding Energies between Homogeneous Oligopeptides.ACS CENTRAL SCIENCE,5(1),97-108.
MLA Du, Huiwen,et al."Principles of Inter-Amino-Acid Recognition Revealed by Binding Energies between Homogeneous Oligopeptides".ACS CENTRAL SCIENCE 5.1(2019):97-108.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Du, Huiwen]'s Articles
[Hu, Xiaoyu]'s Articles
[Duan, Hongyang]'s Articles
Baidu academic
Similar articles in Baidu academic
[Du, Huiwen]'s Articles
[Hu, Xiaoyu]'s Articles
[Duan, Hongyang]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Du, Huiwen]'s Articles
[Hu, Xiaoyu]'s Articles
[Duan, Hongyang]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.