Joint analysis of panel count data with an informative observation process and a dependent terminal event

doi:10.1007/s10985-016-9375-y

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	Joint analysis of panel count data with an informative observation process and a dependent terminal event
	Zhou, Jie 1; Zhang, Haixiang 2; Sun, Liuquan3 ; Sun, Jianguo 4
	2017-10-01
发表期刊	LIFETIME DATA ANALYSIS
ISSN	1380-7870
卷号	23 期号:4 页码:560-584
摘要	Panel count data occur in many clinical and observational studies, and in many situations, the observation process may be informative and also there may exist a terminal event such as death which stops the follow-up. In this article, we propose a new joint model for the analysis of panel count data in the presence of both an informative observation process and a dependent terminal event via two latent variables. For the inference on the proposed models, a class of estimating equations is developed and the resulting estimators are shown to be consistent and asymptotically normal. In addition, a lack-of-fit test is provided for assessing the adequacy of the models. Simulation studies suggest that the proposed approach works well for practical situations. A real example from a bladder cancer clinical trial is used to illustrate the proposed methods.
关键词	Estimating equation Informative observation process Joint modeling Panel count data Terminal event
DOI	10.1007/s10985-016-9375-y
语种	英语
资助项目	National Natural Science Foundation of China[11301355] ; National Natural Science Foundation of China[11301212] ; National Natural Science Foundation of China[11401146] ; National Natural Science Foundation of China[11231010] ; National Natural Science Foundation of China[11171330] ; Key Laboratory of RCSDS ; CAS[2008DP173182] ; BCMIIS
WOS研究方向	Mathematics
WOS类目	Mathematics, Interdisciplinary Applications ; Statistics & Probability
WOS记录号	WOS:000411880000003
出版者	SPRINGER
引用统计
文献类型	期刊论文
条目标识符	http://ir.amss.ac.cn/handle/2S8OKBNM/26655
专题	应用数学研究所
通讯作者	Zhang, Haixiang
作者单位	1.Capital Normal Univ, Sch Math Sci, Beijing 100048, Peoples R China 2.Tianjin Univ, Ctr Appl Math, Tianjin 300072, Peoples R China 3.Chinese Acad Sci, Inst Appl Math, Beijing 100190, Peoples R China 4.Univ Missouri, Dept Stat, Columbia, MO 65211 USA
推荐引用方式 GB/T 7714	Zhou, Jie,Zhang, Haixiang,Sun, Liuquan,et al. Joint analysis of panel count data with an informative observation process and a dependent terminal event[J]. LIFETIME DATA ANALYSIS,2017,23(4):560-584.
APA	Zhou, Jie,Zhang, Haixiang,Sun, Liuquan,&Sun, Jianguo.(2017).Joint analysis of panel count data with an informative observation process and a dependent terminal event.LIFETIME DATA ANALYSIS,23(4),560-584.
MLA	Zhou, Jie,et al."Joint analysis of panel count data with an informative observation process and a dependent terminal event".LIFETIME DATA ANALYSIS 23.4(2017):560-584.