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Joint analysis of panel count data with an informative observation process and a dependent terminal event
Zhou, Jie1; Zhang, Haixiang2; Sun, Liuquan3; Sun, Jianguo4
2017-10-01
Source PublicationLIFETIME DATA ANALYSIS
ISSN1380-7870
Volume23Issue:4Pages:560-584
AbstractPanel count data occur in many clinical and observational studies, and in many situations, the observation process may be informative and also there may exist a terminal event such as death which stops the follow-up. In this article, we propose a new joint model for the analysis of panel count data in the presence of both an informative observation process and a dependent terminal event via two latent variables. For the inference on the proposed models, a class of estimating equations is developed and the resulting estimators are shown to be consistent and asymptotically normal. In addition, a lack-of-fit test is provided for assessing the adequacy of the models. Simulation studies suggest that the proposed approach works well for practical situations. A real example from a bladder cancer clinical trial is used to illustrate the proposed methods.
KeywordEstimating equation Informative observation process Joint modeling Panel count data Terminal event
DOI10.1007/s10985-016-9375-y
Language英语
Funding ProjectNational Natural Science Foundation of China[11301355] ; National Natural Science Foundation of China[11301212] ; National Natural Science Foundation of China[11401146] ; National Natural Science Foundation of China[11231010] ; National Natural Science Foundation of China[11171330] ; Key Laboratory of RCSDS ; CAS[2008DP173182] ; BCMIIS
WOS Research AreaMathematics
WOS SubjectMathematics, Interdisciplinary Applications ; Statistics & Probability
WOS IDWOS:000411880000003
PublisherSPRINGER
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.amss.ac.cn/handle/2S8OKBNM/26655
Collection应用数学研究所
Affiliation1.Capital Normal Univ, Sch Math Sci, Beijing 100048, Peoples R China
2.Tianjin Univ, Ctr Appl Math, Tianjin 300072, Peoples R China
3.Chinese Acad Sci, Inst Appl Math, Beijing 100190, Peoples R China
4.Univ Missouri, Dept Stat, Columbia, MO 65211 USA
Recommended Citation
GB/T 7714
Zhou, Jie,Zhang, Haixiang,Sun, Liuquan,et al. Joint analysis of panel count data with an informative observation process and a dependent terminal event[J]. LIFETIME DATA ANALYSIS,2017,23(4):560-584.
APA Zhou, Jie,Zhang, Haixiang,Sun, Liuquan,&Sun, Jianguo.(2017).Joint analysis of panel count data with an informative observation process and a dependent terminal event.LIFETIME DATA ANALYSIS,23(4),560-584.
MLA Zhou, Jie,et al."Joint analysis of panel count data with an informative observation process and a dependent terminal event".LIFETIME DATA ANALYSIS 23.4(2017):560-584.
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