KMS Of Academy of mathematics and systems sciences, CAS
| Joint modeling of recurrent and terminal events using additive models | |
Qu, Lianqiang1; Sun, Liuquan1 ; Liu, Lei2
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| 2017 | |
| Source Publication | STATISTICS AND ITS INTERFACE
 |
| ISSN | 1938-7989 |
| Volume | 10Issue:4Pages:699-710 |
| Abstract | In this article, we propose a joint modeling approach for the analysis of recurrent event data with a terminal event. We specify an additive rates model with a multiplicative frailty for the conditional recurrent event rate, and an additive hazards frailty model for the terminal event. A shared frailty is used to account for the association between recurrent and terminal events. An estimating equation approach is developed for the marginal and association parameters in the joint model, and the asymptotic properties of the proposed estimators are established. The finite sample performance of the proposed estimators is examined through simulation studies, and an application to a medical cost study of chronic heart failure patients is illustrated. |
| Keyword | Additive models Estimating equations Frailty Partial marginal models Recurrent events Terminal event |
| Language | 英语 |
| Funding Project | National Natural Science Foundation of China[11231010] ; National Natural Science Foundation of China[11171330] ; Key Laboratory of RCSDS ; CAS[2008DP173182] ; BCMIIS ; Agency of Healthcare Research and Quality of USA[R01 HS 020263] |
| WOS Research Area | Mathematical & Computational Biology ; Mathematics |
| WOS Subject | Mathematical & Computational Biology ; Mathematics, Interdisciplinary Applications |
| WOS ID | WOS:000402401300012 |
| Publisher | INT PRESS BOSTON, INC |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.amss.ac.cn/handle/2S8OKBNM/25693 |
| Collection | 应用数学研究所 |
| Corresponding Author | Sun, Liuquan |
| Affiliation | 1.Chinese Acad Sci, Acad Math & Syst Sci, Inst Appl Math, Beijing 100190, Peoples R China 2.Northwestern Univ, Dept Prevent Med, Chicago, IL 60611 USA |
| Recommended Citation GB/T 7714 | Qu, Lianqiang,Sun, Liuquan,Liu, Lei. Joint modeling of recurrent and terminal events using additive models[J]. STATISTICS AND ITS INTERFACE,2017,10(4):699-710. |
| APA | Qu, Lianqiang,Sun, Liuquan,&Liu, Lei.(2017).Joint modeling of recurrent and terminal events using additive models.STATISTICS AND ITS INTERFACE,10(4),699-710. |
| MLA | Qu, Lianqiang,et al."Joint modeling of recurrent and terminal events using additive models".STATISTICS AND ITS INTERFACE 10.4(2017):699-710. |
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