A measuring method of effects of herbs based on classification used for intelligent calculation of efficacies of prescriptions

doi:10.1007/s11432-010-4068-8

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	A measuring method of effects of herbs based on classification used for intelligent calculation of efficacies of prescriptions
	Gao QuanQuan 1; Ren TingGe 2
	2010-10-01
发表期刊	SCIENCE CHINA-INFORMATION SCIENCES
ISSN	1674-733X
卷号	53 期号:10 页码:2047-2061
摘要	It is important to translate dosage of each medical herb in a prescription into intensity of its effects measured by mathematical models. In this paper, we present intelligent calculational algorithms on efficacies of prescriptions of Chinese Medicine (CM), study "how curative effects of any herb depend on dosage" when constructing CM intelligent systems, and discuss relevant issues and definitions. In order to measure intensities of effects of all herbs reasonably, the natural classification method is proposed to classify herbs into 38 natural classes according to their dosage ranges using the knowledge of CM dosage and distribution rules of herbs. Then the 38 natural classes are clustered to 6 basic classes reflecting characteristic attributes of various herbs. Based on the results of classified herbs, a set of nonlinear measuring functions of intensities of effects is designed for various basic classes. These functions have been embedded in our intelligent calculation system of efficacies of prescriptions. The effects of 560 herbs and curative efficacies of more than 1000 prescriptions derived from "ShangHan Lun", "JinGui YaoLue", "Ming Jia Yi An", etc., have been calculated and discovered successfully. It is proved that the accuracy of theses results by these models has been obviously enhanced.
关键词	intelligent calculation mathematical modeling measuring method efficacies of prescriptions
DOI	10.1007/s11432-010-4068-8
语种	英语
资助项目	National Natural Science Foundation of China[60672141] ; National Key Technology R&D Program of China[2007BAI10B06]
WOS研究方向	Computer Science
WOS类目	Computer Science, Information Systems
WOS记录号	WOS:000281670000012
出版者	SCIENCE PRESS
引用统计
文献类型	期刊论文
条目标识符	http://ir.amss.ac.cn/handle/2S8OKBNM/9594
专题	中国科学院数学与系统科学研究院
通讯作者	Gao QuanQuan
作者单位	1.Chinese Acad Sci, Acad Math & Syst, Beijing 100190, Peoples R China 2.Beijing Univ Chinese Med, Beijing 100029, Peoples R China
推荐引用方式 GB/T 7714	Gao QuanQuan,Ren TingGe. A measuring method of effects of herbs based on classification used for intelligent calculation of efficacies of prescriptions[J]. SCIENCE CHINA-INFORMATION SCIENCES,2010,53(10):2047-2061.
APA	Gao QuanQuan,&Ren TingGe.(2010).A measuring method of effects of herbs based on classification used for intelligent calculation of efficacies of prescriptions.SCIENCE CHINA-INFORMATION SCIENCES,53(10),2047-2061.
MLA	Gao QuanQuan,et al."A measuring method of effects of herbs based on classification used for intelligent calculation of efficacies of prescriptions".SCIENCE CHINA-INFORMATION SCIENCES 53.10(2010):2047-2061.