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Variable selection for a mark-specific additive hazards model using the adaptive LASSO
Han, Dongxiao1,2; Qu, Lianqiang3; Sun, Liuquan4,5; Sun, Yanqing6
2021-07-15
发表期刊STATISTICAL METHODS IN MEDICAL RESEARCH
ISSN0962-2802
页码15
摘要In HIV vaccine efficacy trials, mark-specific hazards models have important applications and can be used to evaluate the strain-specific vaccine efficacy. Additive hazards models have been widely used in practice, especially when continuous covariates are present. In this article, we conduct variable selection for a mark-specific additive hazards model. The proposed method is based on an estimating equation with the first derivative of the adaptive LASSO penalty function. The asymptotic properties of the resulting estimators are established. The finite sample behavior of the proposed estimators is evaluated through simulation studies, and an application to a dataset from the first HIV vaccine efficacy trial is provided.
关键词Adaptive LASSO additive hazards model competing risks continuous mark mark-specific vaccine effects survival data
DOI10.1177/09622802211023957
收录类别SCI
语种英语
资助项目Fundamental Research Funds for the Central Universities, Nankai University[9920200110] ; National Natural Science Foundation of China[12001219] ; National Natural Science Foundation of China[11771431] ; National Natural Science Foundation of China[11690015] ; Hubei Natural Science Foundation of China[2018CFB256] ; Key Laboratory of RCSDS, CAS[2008DP173182] ; NIAID NIH[R37AI054165] ; National Science Foundation[DMS1915829]
WOS研究方向Health Care Sciences & Services ; Mathematical & Computational Biology ; Medical Informatics ; Mathematics
WOS类目Health Care Sciences & Services ; Mathematical & Computational Biology ; Medical Informatics ; Statistics & Probability
WOS记录号WOS:000680111700001
出版者SAGE PUBLICATIONS LTD
引用统计
文献类型期刊论文
条目标识符http://ir.amss.ac.cn/handle/2S8OKBNM/59018
专题应用数学研究所
通讯作者Sun, Liuquan
作者单位1.Nankai Univ, LPMC, Sch Stat & Data Sci, Tianjin, Peoples R China
2.Nankai Univ, KLMDASR, Tianjin, Peoples R China
3.Cent China Normal Univ, Sch Math & Stat, Hubei, Peoples R China
4.Chinese Acad Sci, Acad Math & Syst Sci, Inst Appl Math, Beijing, Peoples R China
5.Guangzhou Univ, Sch Econ & Stat, Guangzhou, Peoples R China
6.Univ N Carolina, Dept Math & Stat, Charlotte, NC USA
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Han, Dongxiao,Qu, Lianqiang,Sun, Liuquan,et al. Variable selection for a mark-specific additive hazards model using the adaptive LASSO[J]. STATISTICAL METHODS IN MEDICAL RESEARCH,2021:15.
APA Han, Dongxiao,Qu, Lianqiang,Sun, Liuquan,&Sun, Yanqing.(2021).Variable selection for a mark-specific additive hazards model using the adaptive LASSO.STATISTICAL METHODS IN MEDICAL RESEARCH,15.
MLA Han, Dongxiao,et al."Variable selection for a mark-specific additive hazards model using the adaptive LASSO".STATISTICAL METHODS IN MEDICAL RESEARCH (2021):15.
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