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Variable selection for a mark-specific additive hazards model using the adaptive LASSO
Han, Dongxiao1,2; Qu, Lianqiang3; Sun, Liuquan4,5; Sun, Yanqing6
2021-07-15
Source PublicationSTATISTICAL METHODS IN MEDICAL RESEARCH
ISSN0962-2802
Pages15
AbstractIn HIV vaccine efficacy trials, mark-specific hazards models have important applications and can be used to evaluate the strain-specific vaccine efficacy. Additive hazards models have been widely used in practice, especially when continuous covariates are present. In this article, we conduct variable selection for a mark-specific additive hazards model. The proposed method is based on an estimating equation with the first derivative of the adaptive LASSO penalty function. The asymptotic properties of the resulting estimators are established. The finite sample behavior of the proposed estimators is evaluated through simulation studies, and an application to a dataset from the first HIV vaccine efficacy trial is provided.
KeywordAdaptive LASSO additive hazards model competing risks continuous mark mark-specific vaccine effects survival data
DOI10.1177/09622802211023957
Indexed BySCI
Language英语
Funding ProjectFundamental Research Funds for the Central Universities, Nankai University[9920200110] ; National Natural Science Foundation of China[12001219] ; National Natural Science Foundation of China[11771431] ; National Natural Science Foundation of China[11690015] ; Hubei Natural Science Foundation of China[2018CFB256] ; Key Laboratory of RCSDS, CAS[2008DP173182] ; NIAID NIH[R37AI054165] ; National Science Foundation[DMS1915829]
WOS Research AreaHealth Care Sciences & Services ; Mathematical & Computational Biology ; Medical Informatics ; Mathematics
WOS SubjectHealth Care Sciences & Services ; Mathematical & Computational Biology ; Medical Informatics ; Statistics & Probability
WOS IDWOS:000680111700001
PublisherSAGE PUBLICATIONS LTD
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Document Type期刊论文
Identifierhttp://ir.amss.ac.cn/handle/2S8OKBNM/59018
Collection应用数学研究所
Corresponding AuthorSun, Liuquan
Affiliation1.Nankai Univ, LPMC, Sch Stat & Data Sci, Tianjin, Peoples R China
2.Nankai Univ, KLMDASR, Tianjin, Peoples R China
3.Cent China Normal Univ, Sch Math & Stat, Hubei, Peoples R China
4.Chinese Acad Sci, Acad Math & Syst Sci, Inst Appl Math, Beijing, Peoples R China
5.Guangzhou Univ, Sch Econ & Stat, Guangzhou, Peoples R China
6.Univ N Carolina, Dept Math & Stat, Charlotte, NC USA
Recommended Citation
GB/T 7714
Han, Dongxiao,Qu, Lianqiang,Sun, Liuquan,et al. Variable selection for a mark-specific additive hazards model using the adaptive LASSO[J]. STATISTICAL METHODS IN MEDICAL RESEARCH,2021:15.
APA Han, Dongxiao,Qu, Lianqiang,Sun, Liuquan,&Sun, Yanqing.(2021).Variable selection for a mark-specific additive hazards model using the adaptive LASSO.STATISTICAL METHODS IN MEDICAL RESEARCH,15.
MLA Han, Dongxiao,et al."Variable selection for a mark-specific additive hazards model using the adaptive LASSO".STATISTICAL METHODS IN MEDICAL RESEARCH (2021):15.
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