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A ROC-based test for evaluating the group difference with an application to neonatal audiology screening
Tang, Larry L.1,2; Meng, Zhen3; Li, Qizhai4,5
2021-05-29
Source PublicationSTATISTICS IN MEDICINE
ISSN0277-6715
Pages12
AbstractThis article proposes a powerful method to compare two samples. The proposed method handles comparison of data by drawing inference from ROC curve model parameters. The method estimates parameters from a linear model framework on the empirical sensitivities and specificities. The consistent ROC parameters are then used to give a more powerful test than existing methods in several situations. In addition, we present a comprehensive statistic based on the Cauchy combination, which works well in all scenarios considered in this article. We also offer an efficient one-layer wild permutation procedure to calculate the P-value of our statistic. The method is particularly useful when the underlying continuous biomarker results are non-normal. We illustrate the proposed methods in a neonatal audiology diagnostic example.
KeywordROC curve sensitivity specificity two‐ sample comparison
DOI10.1002/sim.9082
Indexed BySCI
Language英语
Funding ProjectNational Institutes of Health ; US Social Security Administration ; Beijing Natural Science Foundation[Z180006]
WOS Research AreaMathematical & Computational Biology ; Public, Environmental & Occupational Health ; Medical Informatics ; Research & Experimental Medicine ; Mathematics
WOS SubjectMathematical & Computational Biology ; Public, Environmental & Occupational Health ; Medical Informatics ; Medicine, Research & Experimental ; Statistics & Probability
WOS IDWOS:000655879500001
PublisherWILEY
Citation statistics
Document Type期刊论文
Identifierhttp://ir.amss.ac.cn/handle/2S8OKBNM/58699
Collection中国科学院数学与系统科学研究院
Corresponding AuthorTang, Larry L.
Affiliation1.Univ Cent Florida, Dept Stat, Natl Ctr Forens Sci, Orlando, FL 32816 USA
2.NIH, Dept Rehabil Med, Ctr Clin, Bethesda, MD 20892 USA
3.Capital Univ Econ & Business, Sch Stat, Beijing, Peoples R China
4.Chinese Acad Sci, LSC, NCMIS, Acad Math & Syst Sci, Beijing, Peoples R China
5.Univ Chinese Acad Sci, Sch Math Sci, Beijing, Peoples R China
Recommended Citation
GB/T 7714
Tang, Larry L.,Meng, Zhen,Li, Qizhai. A ROC-based test for evaluating the group difference with an application to neonatal audiology screening[J]. STATISTICS IN MEDICINE,2021:12.
APA Tang, Larry L.,Meng, Zhen,&Li, Qizhai.(2021).A ROC-based test for evaluating the group difference with an application to neonatal audiology screening.STATISTICS IN MEDICINE,12.
MLA Tang, Larry L.,et al."A ROC-based test for evaluating the group difference with an application to neonatal audiology screening".STATISTICS IN MEDICINE (2021):12.
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