KMS Of Academy of mathematics and systems sciences, CAS
Inference in a mixture additive hazards cure model | |
Han, Dongxiao1,2; He, Haijin3; Sun, Liuquan4; Song, Xinyuan5; Xu, Wei6,7 | |
2021 | |
发表期刊 | STATISTICS AND ITS INTERFACE |
ISSN | 1938-7989 |
卷号 | 14期号:3页码:323-338 |
摘要 | We propose a mixture additive hazards (AH) cure model for survival data with a cure fraction. The proposed model integrates a logistic regression model for the proportion of patients cured of disease and an AH model for the uncured patients. Generalized estimating equations are developed for parameter estimation, and the asymptotic properties of the resulting estimators are established. In addition, model-checking methods are presented to assess the adequacy of the model. The finite-sample performance of the proposed method is evaluated through simulation studies. An application to a human papillomavirus positive oropharyngeal cancer study is conducted to illustrate the proposed method. |
关键词 | Additive hazards model Cure model Estimating equation Logistic regression Mixture Model checking |
收录类别 | SCI |
语种 | 英语 |
资助项目 | National Natural Science Foundation of China (NSFC)[11701387] ; Natural Science Foundation of Shenzhen[JCYJ20190808173603590] ; Natural Science Foundation of Shenzhen[JCYJ20170817100950436] ; NSFC[11771431] ; NSFC[11690015] ; Key Laboratory of RCSDS, CAS[2008DP173182] ; Research Grant Council of the HKSAR[14301918] ; Research Grant Council of the HKSAR[14303017] ; Canadian Institute of Health Research[145546] ; Natural Science and Engineering Research Council of Canada[RGPIN-2017-06672] ; Chinese University of Hong Kong |
WOS研究方向 | Mathematical & Computational Biology ; Mathematics |
WOS类目 | Mathematical & Computational Biology ; Mathematics, Interdisciplinary Applications |
WOS记录号 | WOS:000617450600008 |
出版者 | INT PRESS BOSTON, INC |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.amss.ac.cn/handle/2S8OKBNM/58180 |
专题 | 应用数学研究所 |
通讯作者 | He, Haijin |
作者单位 | 1.Nankai Univ, Sch Stat & Data Sci, LPMC, Tianjin, Peoples R China 2.Nankai Univ, KLMDASR, Tianjin, Peoples R China 3.Shenzhen Univ, Coll Math & Stat, Shenzhen Key Lab Adv Machine Learning & Applicat, Shenzhen, Peoples R China 4.Chinese Acad Sci, Acad Math & Syst Sci, Inst Appl Math, Beijing, Peoples R China 5.Chinese Univ Hong Kong, Dept Stat, Hong Kong, Peoples R China 6.Univ Toronto, Princess Margaret Canc Ctr, Dept Biostat, Toronto, ON, Canada 7.Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, Canada |
推荐引用方式 GB/T 7714 | Han, Dongxiao,He, Haijin,Sun, Liuquan,et al. Inference in a mixture additive hazards cure model[J]. STATISTICS AND ITS INTERFACE,2021,14(3):323-338. |
APA | Han, Dongxiao,He, Haijin,Sun, Liuquan,Song, Xinyuan,&Xu, Wei.(2021).Inference in a mixture additive hazards cure model.STATISTICS AND ITS INTERFACE,14(3),323-338. |
MLA | Han, Dongxiao,et al."Inference in a mixture additive hazards cure model".STATISTICS AND ITS INTERFACE 14.3(2021):323-338. |
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