KMS Of Academy of mathematics and systems sciences, CAS
Inference in a mixture additive hazards cure model | |
Han, Dongxiao1,2; He, Haijin3; Sun, Liuquan4![]() | |
2021 | |
Source Publication | STATISTICS AND ITS INTERFACE
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ISSN | 1938-7989 |
Volume | 14Issue:3Pages:323-338 |
Abstract | We propose a mixture additive hazards (AH) cure model for survival data with a cure fraction. The proposed model integrates a logistic regression model for the proportion of patients cured of disease and an AH model for the uncured patients. Generalized estimating equations are developed for parameter estimation, and the asymptotic properties of the resulting estimators are established. In addition, model-checking methods are presented to assess the adequacy of the model. The finite-sample performance of the proposed method is evaluated through simulation studies. An application to a human papillomavirus positive oropharyngeal cancer study is conducted to illustrate the proposed method. |
Keyword | Additive hazards model Cure model Estimating equation Logistic regression Mixture Model checking |
Indexed By | SCI |
Language | 英语 |
Funding Project | National Natural Science Foundation of China (NSFC)[11701387] ; Natural Science Foundation of Shenzhen[JCYJ20190808173603590] ; Natural Science Foundation of Shenzhen[JCYJ20170817100950436] ; NSFC[11771431] ; NSFC[11690015] ; Key Laboratory of RCSDS, CAS[2008DP173182] ; Research Grant Council of the HKSAR[14301918] ; Research Grant Council of the HKSAR[14303017] ; Canadian Institute of Health Research[145546] ; Natural Science and Engineering Research Council of Canada[RGPIN-2017-06672] ; Chinese University of Hong Kong |
WOS Research Area | Mathematical & Computational Biology ; Mathematics |
WOS Subject | Mathematical & Computational Biology ; Mathematics, Interdisciplinary Applications |
WOS ID | WOS:000617450600008 |
Publisher | INT PRESS BOSTON, INC |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.amss.ac.cn/handle/2S8OKBNM/58180 |
Collection | 应用数学研究所 |
Corresponding Author | He, Haijin |
Affiliation | 1.Nankai Univ, Sch Stat & Data Sci, LPMC, Tianjin, Peoples R China 2.Nankai Univ, KLMDASR, Tianjin, Peoples R China 3.Shenzhen Univ, Coll Math & Stat, Shenzhen Key Lab Adv Machine Learning & Applicat, Shenzhen, Peoples R China 4.Chinese Acad Sci, Acad Math & Syst Sci, Inst Appl Math, Beijing, Peoples R China 5.Chinese Univ Hong Kong, Dept Stat, Hong Kong, Peoples R China 6.Univ Toronto, Princess Margaret Canc Ctr, Dept Biostat, Toronto, ON, Canada 7.Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, Canada |
Recommended Citation GB/T 7714 | Han, Dongxiao,He, Haijin,Sun, Liuquan,et al. Inference in a mixture additive hazards cure model[J]. STATISTICS AND ITS INTERFACE,2021,14(3):323-338. |
APA | Han, Dongxiao,He, Haijin,Sun, Liuquan,Song, Xinyuan,&Xu, Wei.(2021).Inference in a mixture additive hazards cure model.STATISTICS AND ITS INTERFACE,14(3),323-338. |
MLA | Han, Dongxiao,et al."Inference in a mixture additive hazards cure model".STATISTICS AND ITS INTERFACE 14.3(2021):323-338. |
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