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Inference in a mixture additive hazards cure model
Han, Dongxiao1,2; He, Haijin3; Sun, Liuquan4; Song, Xinyuan5; Xu, Wei6,7
2021
发表期刊STATISTICS AND ITS INTERFACE
ISSN1938-7989
卷号14期号:3页码:323-338
摘要We propose a mixture additive hazards (AH) cure model for survival data with a cure fraction. The proposed model integrates a logistic regression model for the proportion of patients cured of disease and an AH model for the uncured patients. Generalized estimating equations are developed for parameter estimation, and the asymptotic properties of the resulting estimators are established. In addition, model-checking methods are presented to assess the adequacy of the model. The finite-sample performance of the proposed method is evaluated through simulation studies. An application to a human papillomavirus positive oropharyngeal cancer study is conducted to illustrate the proposed method.
关键词Additive hazards model Cure model Estimating equation Logistic regression Mixture Model checking
收录类别SCI
语种英语
资助项目National Natural Science Foundation of China (NSFC)[11701387] ; Natural Science Foundation of Shenzhen[JCYJ20190808173603590] ; Natural Science Foundation of Shenzhen[JCYJ20170817100950436] ; NSFC[11771431] ; NSFC[11690015] ; Key Laboratory of RCSDS, CAS[2008DP173182] ; Research Grant Council of the HKSAR[14301918] ; Research Grant Council of the HKSAR[14303017] ; Canadian Institute of Health Research[145546] ; Natural Science and Engineering Research Council of Canada[RGPIN-2017-06672] ; Chinese University of Hong Kong
WOS研究方向Mathematical & Computational Biology ; Mathematics
WOS类目Mathematical & Computational Biology ; Mathematics, Interdisciplinary Applications
WOS记录号WOS:000617450600008
出版者INT PRESS BOSTON, INC
引用统计
文献类型期刊论文
条目标识符http://ir.amss.ac.cn/handle/2S8OKBNM/58180
专题应用数学研究所
通讯作者He, Haijin
作者单位1.Nankai Univ, Sch Stat & Data Sci, LPMC, Tianjin, Peoples R China
2.Nankai Univ, KLMDASR, Tianjin, Peoples R China
3.Shenzhen Univ, Coll Math & Stat, Shenzhen Key Lab Adv Machine Learning & Applicat, Shenzhen, Peoples R China
4.Chinese Acad Sci, Acad Math & Syst Sci, Inst Appl Math, Beijing, Peoples R China
5.Chinese Univ Hong Kong, Dept Stat, Hong Kong, Peoples R China
6.Univ Toronto, Princess Margaret Canc Ctr, Dept Biostat, Toronto, ON, Canada
7.Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, Canada
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GB/T 7714
Han, Dongxiao,He, Haijin,Sun, Liuquan,et al. Inference in a mixture additive hazards cure model[J]. STATISTICS AND ITS INTERFACE,2021,14(3):323-338.
APA Han, Dongxiao,He, Haijin,Sun, Liuquan,Song, Xinyuan,&Xu, Wei.(2021).Inference in a mixture additive hazards cure model.STATISTICS AND ITS INTERFACE,14(3),323-338.
MLA Han, Dongxiao,et al."Inference in a mixture additive hazards cure model".STATISTICS AND ITS INTERFACE 14.3(2021):323-338.
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