A semiparametric additive rates model for the weighted composite endpoint of recurrent and terminal events

doi:10.1007/s10985-019-09486-w

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	A semiparametric additive rates model for the weighted composite endpoint of recurrent and terminal events
	Sun, Xiaowei 1,2; Ding, Jieli 3; Sun, Liuquan1,2
	2020-07-01
Source Publication	LIFETIME DATA ANALYSIS
ISSN	1380-7870
Volume	26 Issue:3 Pages:471-492
Abstract	Recurrent event data with a terminal event commonly arise in longitudinal follow-up studies. We use a weighted composite endpoint of all recurrent and terminal events to assess the overall effects of covariates on the two types of events. A semiparametric additive rates model is proposed to analyze the weighted composite event process and the dependence structure among recurrent and terminal events is left unspecified. An estimating equation approach is developed for inference, and the asymptotic properties of the resulting estimators are established. The finite-sample behavior of the proposed estimators is evaluated through simulation studies, and an application to a bladder cancer study is illustrated.
Keyword	Additive rates model Estimating equations Recurrent events Terminal event Weighted composite endpoint
DOI	10.1007/s10985-019-09486-w
Indexed By	SCI
Language	英语
WOS Research Area	Mathematics
WOS Subject	Mathematics, Interdisciplinary Applications ; Statistics & Probability
WOS ID	WOS:000535415700002
Publisher	SPRINGER
Citation statistics
Document Type	期刊论文
Identifier	http://ir.amss.ac.cn/handle/2S8OKBNM/51507
Collection	应用数学研究所
Corresponding Author	Sun, Liuquan
Affiliation	1.Chinese Acad Sci, Acad Math & Syst Sci, Inst Appl Math, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Wuhan Univ, Sch Math & Stat, Wuhan 430072, Hubei, Peoples R China
Recommended Citation GB/T 7714	Sun, Xiaowei,Ding, Jieli,Sun, Liuquan. A semiparametric additive rates model for the weighted composite endpoint of recurrent and terminal events[J]. LIFETIME DATA ANALYSIS,2020,26(3):471-492.
APA	Sun, Xiaowei,Ding, Jieli,&Sun, Liuquan.(2020).A semiparametric additive rates model for the weighted composite endpoint of recurrent and terminal events.LIFETIME DATA ANALYSIS,26(3),471-492.
MLA	Sun, Xiaowei,et al."A semiparametric additive rates model for the weighted composite endpoint of recurrent and terminal events".LIFETIME DATA ANALYSIS 26.3(2020):471-492.

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