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A semiparametric additive rates model for the weighted composite endpoint of recurrent and terminal events
Sun, Xiaowei1,2; Ding, Jieli3; Sun, Liuquan1,2
2020-07-01
Source PublicationLIFETIME DATA ANALYSIS
ISSN1380-7870
Volume26Issue:3Pages:471-492
AbstractRecurrent event data with a terminal event commonly arise in longitudinal follow-up studies. We use a weighted composite endpoint of all recurrent and terminal events to assess the overall effects of covariates on the two types of events. A semiparametric additive rates model is proposed to analyze the weighted composite event process and the dependence structure among recurrent and terminal events is left unspecified. An estimating equation approach is developed for inference, and the asymptotic properties of the resulting estimators are established. The finite-sample behavior of the proposed estimators is evaluated through simulation studies, and an application to a bladder cancer study is illustrated.
KeywordAdditive rates model Estimating equations Recurrent events Terminal event Weighted composite endpoint
DOI10.1007/s10985-019-09486-w
Indexed BySCI
Language英语
WOS Research AreaMathematics
WOS SubjectMathematics, Interdisciplinary Applications ; Statistics & Probability
WOS IDWOS:000535415700002
PublisherSPRINGER
Citation statistics
Document Type期刊论文
Identifierhttp://ir.amss.ac.cn/handle/2S8OKBNM/51507
Collection中国科学院数学与系统科学研究院
Corresponding AuthorSun, Liuquan
Affiliation1.Chinese Acad Sci, Acad Math & Syst Sci, Inst Appl Math, Beijing 100190, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Wuhan Univ, Sch Math & Stat, Wuhan 430072, Hubei, Peoples R China
Recommended Citation
GB/T 7714
Sun, Xiaowei,Ding, Jieli,Sun, Liuquan. A semiparametric additive rates model for the weighted composite endpoint of recurrent and terminal events[J]. LIFETIME DATA ANALYSIS,2020,26(3):471-492.
APA Sun, Xiaowei,Ding, Jieli,&Sun, Liuquan.(2020).A semiparametric additive rates model for the weighted composite endpoint of recurrent and terminal events.LIFETIME DATA ANALYSIS,26(3),471-492.
MLA Sun, Xiaowei,et al."A semiparametric additive rates model for the weighted composite endpoint of recurrent and terminal events".LIFETIME DATA ANALYSIS 26.3(2020):471-492.
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