Models and algorithms for haplotyping problem

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	Models and algorithms for haplotyping problem
	Zhang, Xiang-Sun; Wang, Rui-Sheng ; Wu, Ling-Yun ; Chen, Luonan
	2006
发表期刊	CURRENT BIOINFORMATICS
ISSN	1574-8936
卷号	1 期号:1 页码:105-114
摘要	One of the main topics in genomics is to determine the relevance of DNA variations with some genetic disease. Single nucleotide polymorphism (SNP) is the most frequent and important form of genetic variation which involves a single DNA base. The values of a set of SNPs on a particular chromosome copy define a haplotype. Because of its importance in the studies of complex disease association, haplotyping is one of the central problems in bioinformatics. There are two classes of in silico haplotyping problems, i.e., single individual haplotyping and population haplotyping. In this review paper, we give an overview on the existing models and algorithms on this topic, report the recent. progresses from the computational viewpoint and further discuss the future research trends.
语种	英语
WOS研究方向	Biochemistry & Molecular Biology ; Mathematical & Computational Biology
WOS类目	Biochemical Research Methods ; Mathematical & Computational Biology
WOS记录号	WOS:000244372700011
出版者	BENTHAM SCIENCE PUBL LTD
引用统计
文献类型	期刊论文
条目标识符	http://ir.amss.ac.cn/handle/2S8OKBNM/2840
专题	应用数学研究所
通讯作者	Chen, Luonan
作者单位	1.Osaka Sangyo Univ, Dept Elect Engn & Elect, Osaka 5748530, Japan 2.Chinese Acad Sci, Inst Appl Math, Acad Math & Syst Sci, Beijing 100080, Peoples R China 3.Renmin Univ China, Sch Informat, Beijing 100872, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Xiang-Sun,Wang, Rui-Sheng,Wu, Ling-Yun,et al. Models and algorithms for haplotyping problem[J]. CURRENT BIOINFORMATICS,2006,1(1):105-114.
APA	Zhang, Xiang-Sun,Wang, Rui-Sheng,Wu, Ling-Yun,&Chen, Luonan.(2006).Models and algorithms for haplotyping problem.CURRENT BIOINFORMATICS,1(1),105-114.
MLA	Zhang, Xiang-Sun,et al."Models and algorithms for haplotyping problem".CURRENT BIOINFORMATICS 1.1(2006):105-114.