KMS Of Academy of mathematics and systems sciences, CAS
| Models and algorithms for haplotyping problem | |
Zhang, Xiang-Sun ; Wang, Rui-Sheng; Wu, Ling-Yun; Chen, Luonan
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| 2006 | |
| Source Publication | CURRENT BIOINFORMATICS
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| ISSN | 1574-8936 |
| Volume | 1Issue:1Pages:105-114 |
| Abstract | One of the main topics in genomics is to determine the relevance of DNA variations with some genetic disease. Single nucleotide polymorphism (SNP) is the most frequent and important form of genetic variation which involves a single DNA base. The values of a set of SNPs on a particular chromosome copy define a haplotype. Because of its importance in the studies of complex disease association, haplotyping is one of the central problems in bioinformatics. There are two classes of in silico haplotyping problems, i.e., single individual haplotyping and population haplotyping. In this review paper, we give an overview on the existing models and algorithms on this topic, report the recent. progresses from the computational viewpoint and further discuss the future research trends. |
| Language | 英语 |
| WOS Research Area | Biochemistry & Molecular Biology ; Mathematical & Computational Biology |
| WOS Subject | Biochemical Research Methods ; Mathematical & Computational Biology |
| WOS ID | WOS:000244372700011 |
| Publisher | BENTHAM SCIENCE PUBL LTD |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.amss.ac.cn/handle/2S8OKBNM/2840 |
| Collection | 应用数学研究所 |
| Corresponding Author | Chen, Luonan |
| Affiliation | 1.Osaka Sangyo Univ, Dept Elect Engn & Elect, Osaka 5748530, Japan 2.Chinese Acad Sci, Inst Appl Math, Acad Math & Syst Sci, Beijing 100080, Peoples R China 3.Renmin Univ China, Sch Informat, Beijing 100872, Peoples R China |
| Recommended Citation GB/T 7714 | Zhang, Xiang-Sun,Wang, Rui-Sheng,Wu, Ling-Yun,et al. Models and algorithms for haplotyping problem[J]. CURRENT BIOINFORMATICS,2006,1(1):105-114. |
| APA | Zhang, Xiang-Sun,Wang, Rui-Sheng,Wu, Ling-Yun,&Chen, Luonan.(2006).Models and algorithms for haplotyping problem.CURRENT BIOINFORMATICS,1(1),105-114. |
| MLA | Zhang, Xiang-Sun,et al."Models and algorithms for haplotyping problem".CURRENT BIOINFORMATICS 1.1(2006):105-114. |
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