Automatic classification of protein structures based on convex hull representation by integrated neural network

CSpace > 应用数学研究所

	Automatic classification of protein structures based on convex hull representation by integrated neural network
	Wang, Yong; Wu, Ling-Yun; Zhang, Xiang-Sun; Chen, Luonan
	2006
发表期刊	THEORY AND APPLICATIONS OF MODELS OF COMPUTATION, PROCEEDINGS
ISSN	0302-9743
卷号	3959 页码:505-514
摘要	The large scale deposited data and existing manual classification scheme make it possible to study the automatic classification of protein structures in machine learning framework. In this paper the classification system is constructed by an integrated feedforward neural network through incorporating the expert judgements and existing classification schemes into the learning procedure. Since different aspects of a protein structure may be relevant to various biological problems, the protein structure is represented by the convex hull of its backbone and geometric features are extracted. The training and prediction tests for different training sets in the class level of CATH indicate that the new automatic classification scheme is effective and efficient. Also the neural network model outperforms hidden markov model and support vector machine in the comparison experiment.
语种	英语
WOS研究方向	Computer Science ; Mathematics
WOS类目	Computer Science, Theory & Methods ; Mathematics, Applied
WOS记录号	WOS:000238091800048
出版者	SPRINGER-VERLAG BERLIN
引用统计
文献类型	期刊论文
条目标识符	http://ir.amss.ac.cn/handle/2S8OKBNM/2597
专题	应用数学研究所
通讯作者	Wang, Yong
作者单位	1.Osaka Sangyo Univ, Osaka 5748530, Japan 2.CAS, Acad Math & Syst Sci, Beijing 100080, Peoples R China
推荐引用方式 GB/T 7714	Wang, Yong,Wu, Ling-Yun,Zhang, Xiang-Sun,et al. Automatic classification of protein structures based on convex hull representation by integrated neural network[J]. THEORY AND APPLICATIONS OF MODELS OF COMPUTATION, PROCEEDINGS,2006,3959:505-514.
APA	Wang, Yong,Wu, Ling-Yun,Zhang, Xiang-Sun,&Chen, Luonan.(2006).Automatic classification of protein structures based on convex hull representation by integrated neural network.THEORY AND APPLICATIONS OF MODELS OF COMPUTATION, PROCEEDINGS,3959,505-514.
MLA	Wang, Yong,et al."Automatic classification of protein structures based on convex hull representation by integrated neural network".THEORY AND APPLICATIONS OF MODELS OF COMPUTATION, PROCEEDINGS 3959(2006):505-514.