Protein structure comparison based on a measure of information discrepancy

CSpace > 应用数学研究所

	Protein structure comparison based on a measure of information discrepancy
	Wu, Zi-Kai ; Wang, Yong; Feng, En-Min ; Zhao, Jin-Cheng
	2006
发表期刊	THEORY AND APPLICATIONS OF MODELS OF COMPUTATION, PROCEEDINGS
ISSN	0302-9743
卷号	3959 页码:515-527
摘要	Protein structure comparison is an important tool to explore and understand the different aspects of protein 3D structures. In this paper, a novel representation of protein structure (complete information set of C-alpha - C-alpha distances, CISD) is formulated at first. Then an FDOD score scheme is developed to measure the similarity between two representations. Numerical experiments of the new method are conducted in four different protein datasets and clustering analyses are given to verify the effectiveness of this new similarity measure. Furthermore, preliminary results of detecting homologous protein pairs of an existing non-redundant subset of CATH v2.5.1 based on the new similarity are given as a pilot study. All the results show that this new approach to measure the similarities between protein structures is simple to implement, computationally efficient and fast.
语种	英语
WOS研究方向	Computer Science ; Mathematics
WOS类目	Computer Science, Theory & Methods ; Mathematics, Applied
WOS记录号	WOS:000238091800049
出版者	SPRINGER-VERLAG BERLIN
引用统计
文献类型	期刊论文
条目标识符	http://ir.amss.ac.cn/handle/2S8OKBNM/2471
专题	应用数学研究所
通讯作者	Wu, Zi-Kai
作者单位	1.Dalian Univ Technol, Dept Appl Math, Dalian 116024, Peoples R China 2.CAS, Acad Math & Syst Sci, Inst Appl Math, Beijing 100080, Peoples R China 3.Osaka Sangyo Univ, Osaka 5748530, Japan 4.Dalian Univ, Inst Bioinformat & Mol Design, Dalian 116022, Peoples R China
推荐引用方式 GB/T 7714	Wu, Zi-Kai,Wang, Yong,Feng, En-Min,et al. Protein structure comparison based on a measure of information discrepancy[J]. THEORY AND APPLICATIONS OF MODELS OF COMPUTATION, PROCEEDINGS,2006,3959:515-527.
APA	Wu, Zi-Kai,Wang, Yong,Feng, En-Min,&Zhao, Jin-Cheng.(2006).Protein structure comparison based on a measure of information discrepancy.THEORY AND APPLICATIONS OF MODELS OF COMPUTATION, PROCEEDINGS,3959,515-527.
MLA	Wu, Zi-Kai,et al."Protein structure comparison based on a measure of information discrepancy".THEORY AND APPLICATIONS OF MODELS OF COMPUTATION, PROCEEDINGS 3959(2006):515-527.