A mechanism of synchronization in interacting multi-cell genetic systems

doi:10.1016/j.physd.2005.08.008

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	A mechanism of synchronization in interacting multi-cell genetic systems
	Zhou, TS ; Chen, LN ; Wang, RQ
	2005-11-01
发表期刊	PHYSICA D-NONLINEAR PHENOMENA
ISSN	0167-2789
卷号	211 期号:1-2 页码:107-127
摘要	We investigate a general coupled noisy system with time delays, which may be applied to biologically plausible systems for cell-cell communication in a simplified context. The main conclusion is that appropriate noise intensities and coupling strengths are capable of driving the system to be synchronous. We first provide an analytical treatment for the synchronization process, based on the essential phase-locking mechanism, and then derive sufficient conditions which, if satisfied, ensure existence of the synchrony solution. Finally, a multi-cell system with a synthetic gene regulatory network, which contains both intracellular and extracellular noises and time delays, is adopted to demonstrate effects of extracellular noises and couplings on synchronization. (c) 2005 Elsevier B.V. All rights reserved.
关键词	synchronization gene regulatory network stochastic differential equation global Hopf bifurcation theorem
DOI	10.1016/j.physd.2005.08.008
语种	英语
WOS研究方向	Mathematics ; Physics
WOS类目	Mathematics, Applied ; Physics, Multidisciplinary ; Physics, Mathematical
WOS记录号	WOS:000232727200008
出版者	ELSEVIER SCIENCE BV
引用统计
文献类型	期刊论文
条目标识符	http://ir.amss.ac.cn/handle/2S8OKBNM/1241
专题	中国科学院数学与系统科学研究院
作者单位	1.Zhongshan Univ, Dept Math & Computat Sci, Guangzhou 510275, Peoples R China 2.Osaka Sangyo Univ, Dept Elect Engn & Elect, Daito, Osaka 5748530, Japan 3.Chinese Acad Sci, Acad Math & Syst Sci, Beijing 100080, Peoples R China
推荐引用方式 GB/T 7714	Zhou, TS,Chen, LN,Wang, RQ. A mechanism of synchronization in interacting multi-cell genetic systems[J]. PHYSICA D-NONLINEAR PHENOMENA,2005,211(1-2):107-127.
APA	Zhou, TS,Chen, LN,&Wang, RQ.(2005).A mechanism of synchronization in interacting multi-cell genetic systems.PHYSICA D-NONLINEAR PHENOMENA,211(1-2),107-127.
MLA	Zhou, TS,et al."A mechanism of synchronization in interacting multi-cell genetic systems".PHYSICA D-NONLINEAR PHENOMENA 211.1-2(2005):107-127.