Linear regression analysis of survival data with missing censoring indicators

doi:10.1007/s10985-010-9175-8

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	Linear regression analysis of survival data with missing censoring indicators
	Wang, Qihua2,3 ; Dinse, Gregg E.1
	2011-04-01
发表期刊	LIFETIME DATA ANALYSIS
ISSN	1380-7870
卷号	17 期号:2 页码:256-279
摘要	Linear regression analysis has been studied extensively in a random censorship setting, but typically all of the censoring indicators are assumed to be observed. In this paper, we develop synthetic data methods for estimating regression parameters in a linear model when some censoring indicators are missing. We define estimators based on regression calibration, imputation, and inverse probability weighting techniques, and we prove all three estimators are asymptotically normal. The finite-sample performance of each estimator is evaluated via simulation. We illustrate our methods by assessing the effects of sex and age on the time to non-ambulatory progression for patients in a brain cancer clinical trial.
关键词	Asymptotic normality Censoring indicator Imputation Inverse probability weighting Least squares Missing at random Regression calibration
DOI	10.1007/s10985-010-9175-8
语种	英语
资助项目	National Science Fund for Distinguished Young Scholars in China[10725106] ; National Natural Science Foundation of China[10671198] ; National Science Fund for Creative Research Groups in China ; research Grants Council of Hong Kong[HKU 7050/06P] ; Key Lab of Random Complex Structures and Data Science, CAS ; NIH, National Institute of Environmental Health Sciences[Z01-ES-045007-13]
WOS研究方向	Mathematics
WOS类目	Mathematics, Interdisciplinary Applications ; Statistics & Probability
WOS记录号	WOS:000287664500005
出版者	SPRINGER
引用统计
文献类型	期刊论文
条目标识符	http://ir.amss.ac.cn/handle/2S8OKBNM/12076
专题	应用数学研究所
通讯作者	Dinse, Gregg E.
作者单位	1.NIEHS, Biostat Branch, Res Triangle Pk, NC 27709 USA 2.Yunnan Univ, Dept Math & Stat, Kunming 650091, Peoples R China 3.Chinese Acad Sci, Acad Math & Syst Sci, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Wang, Qihua,Dinse, Gregg E.. Linear regression analysis of survival data with missing censoring indicators[J]. LIFETIME DATA ANALYSIS,2011,17(2):256-279.
APA	Wang, Qihua,&Dinse, Gregg E..(2011).Linear regression analysis of survival data with missing censoring indicators.LIFETIME DATA ANALYSIS,17(2),256-279.
MLA	Wang, Qihua,et al."Linear regression analysis of survival data with missing censoring indicators".LIFETIME DATA ANALYSIS 17.2(2011):256-279.