Single-particle reconstruction using L-2-gradient flow

doi:10.1016/j.jsb.2011.08.005

	Single-particle reconstruction using L-2-gradient flow
	Li, Ming1,2 ; Xu, Guoliang 1; Sorzano, Carlos O. S.3; Sun, Fei 2; Bajaj, Chandrajit L.4,5
	2011-12-01
发表期刊	JOURNAL OF STRUCTURAL BIOLOGY
ISSN	1047-8477
卷号	176 期号:3 页码:259-267
摘要	In this paper, we present an iterative algorithm for reconstructing a three-dimensional density function from a set of two dimensional electron microscopy images. By minimizing an energy functional consisting of a fidelity term and a regularization term, an L-2-gradient flow is derived. The flow is integrated by a finite element method in the spatial direction and an explicit Euler scheme in the temporal direction. Our method compares favorably with those of the weighted back projection, Fourier method, algebraic reconstruction technique and simultaneous iterative reconstruction technique. (C) 2011 Elsevier Inc. All rights reserved.
关键词	L-2-gradient flow Reconstruction Electron microscopy Single-particle analysis
DOI	10.1016/j.jsb.2011.08.005
语种	英语
资助项目	NSFC[60773165] ; NSFC[10990013] ; NSFC[30721003] ; Creative Research Groups of China[11021101] ; Ramon y Cajal ; European Social Fund ; Ministerio de Ciencia e Innovacin ; Chinese Academy of Sciences[KGCX1-YW-13] ; Chinese Academy of Sciences[KSCX2-EW-J-3] ; "973" project[2011CB910301] ; NIH[R01-EB004873] ; NIH[R01-GM074258]
WOS研究方向	Biochemistry & Molecular Biology ; Biophysics ; Cell Biology
WOS类目	Biochemistry & Molecular Biology ; Biophysics ; Cell Biology
WOS记录号	WOS:000297089000001
出版者	ACADEMIC PRESS INC ELSEVIER SCIENCE
引用统计
文献类型	期刊论文
条目标识符	http://ir.amss.ac.cn/handle/2S8OKBNM/11950
专题	计算数学与科学工程计算研究所
通讯作者	Xu, Guoliang
作者单位	1.Chinese Acad Sci, Acad Math & Syst Sci, LSEC, Inst Computat Math & Sci Engn, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Inst Biophys, Natl Lab Biomacromol, Beijing 100190, Peoples R China 3.Natl Ctr Biotechnol CSIC, Biocomp Unit, Madrid, Spain 4.Univ Texas Austin, Dept Comp Sci, Austin, TX 78712 USA 5.Univ Texas Austin, Inst Computat Engn & Sci, Austin, TX 78712 USA
推荐引用方式 GB/T 7714	Li, Ming,Xu, Guoliang,Sorzano, Carlos O. S.,et al. Single-particle reconstruction using L-2-gradient flow[J]. JOURNAL OF STRUCTURAL BIOLOGY,2011,176(3):259-267.
APA	Li, Ming,Xu, Guoliang,Sorzano, Carlos O. S.,Sun, Fei,&Bajaj, Chandrajit L..(2011).Single-particle reconstruction using L-2-gradient flow.JOURNAL OF STRUCTURAL BIOLOGY,176(3),259-267.
MLA	Li, Ming,et al."Single-particle reconstruction using L-2-gradient flow".JOURNAL OF STRUCTURAL BIOLOGY 176.3(2011):259-267.