Continuum electromechanical modeling of protein-membrane interactions

doi:10.1103/PhysRevE.82.041923

	Continuum electromechanical modeling of protein-membrane interactions
	Zhou, Y. C.1; Lu, Benzhuo2 ; Gorfe, Alemayehu A.3
	2010-10-28
发表期刊	PHYSICAL REVIEW E
ISSN	1539-3755
卷号	82 期号:4 页码:5
摘要	A continuum electromechanical model is proposed to describe the membrane curvature induced by electrostatic interactions in a solvated protein-membrane system. The model couples the macroscopic strain energy of membrane and the electrostatic solvation energy of the system, and equilibrium membrane deformation is obtained by minimizing the electroelastic energy functional with respect to the dielectric interface. The model is illustrated with the systems with increasing geometry complexity and captures the sensitivity of membrane curvature to the permanent and mobile charge distributions.
DOI	10.1103/PhysRevE.82.041923
语种	英语
资助项目	Colorado State University ; Chinese Academy of Sciences ; State Key Laboratory of Scientific/Engineering Computing ; NSFC[NSFC10971218] ; University of Texas Medical School at Houston
WOS研究方向	Physics
WOS类目	Physics, Fluids & Plasmas ; Physics, Mathematical
WOS记录号	WOS:000283579900009
出版者	AMER PHYSICAL SOC
引用统计
文献类型	期刊论文
条目标识符	http://ir.amss.ac.cn/handle/2S8OKBNM/10055
专题	计算数学与科学工程计算研究所
通讯作者	Zhou, Y. C.
作者单位	1.Colorado State Univ, Dept Math, Ft Collins, CO 80523 USA 2.Chinese Acad Sci, State Key Lab Sci Engn Comp, Inst Computat Math & Sci Engn Comp, Beijing 100190, Peoples R China 3.Univ Texas Med Sch Houston, Dept Integrat Biol & Pharmacol, Houston, TX 77225 USA
推荐引用方式 GB/T 7714	Zhou, Y. C.,Lu, Benzhuo,Gorfe, Alemayehu A.. Continuum electromechanical modeling of protein-membrane interactions[J]. PHYSICAL REVIEW E,2010,82(4):5.
APA	Zhou, Y. C.,Lu, Benzhuo,&Gorfe, Alemayehu A..(2010).Continuum electromechanical modeling of protein-membrane interactions.PHYSICAL REVIEW E,82(4),5.
MLA	Zhou, Y. C.,et al."Continuum electromechanical modeling of protein-membrane interactions".PHYSICAL REVIEW E 82.4(2010):5.