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A Branch Point on Differentiation Trajectory is the Bifurcating Event Revealed by Dynamical Network Biomarker Analysis of Single-Cell Data 期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2020, 卷号: 17, 期号: 2, 页码: 366-375
Authors:  Chen, Ziwei;  Bai, Xiangqi;  Ma, Liang;  Wang, Xiawei;  Liu, Xiuqin;  Liu, Yuting;  Chen, Luonan;  Wan, Lin
Favorite  |  View/Download:2/0  |  Submit date:2020/05/24
Trajectory  Heuristic algorithms  Mice  Correlation  Reactive power  Pseudo temporal trajectory  branch point  DNB theory  reconstruction  single-cell data  bifurcation  dynamical system  
Multi-scale analysis of schizophrenia risk genes, brain structure, and clinical symptoms reveals integrative clues for subtyping schizophrenia patients 期刊论文
JOURNAL OF MOLECULAR CELL BIOLOGY, 2019, 卷号: 11, 期号: 8, 页码: 678-687
Authors:  Ma, Liang;  Rolls, Edmund T.;  Liu, Xiuqin;  Liu, Yuting;  Jiao, Zeyu;  Wang, Yue;  Gong, Weikang;  Ma, Zhiming;  Gong, Fuzhou;  Wan, Lin
Favorite  |  View/Download:3/0  |  Submit date:2020/05/24
Schizophrenia  PANSS  multi-scale analysis  hot cluster  grey matter volume  pathway  
TSEE: an elastic embedding method to visualize the dynamic gene expression patterns of time series single-cell RNA sequencing data 期刊论文
BMC GENOMICS, 2019, 卷号: 20, 页码: 16
Authors:  An, Shaokun;  Ma, Liang;  Wan, Lin
Favorite  |  View/Download:5/0  |  Submit date:2019/10/28
Nonlinear dimensionality reduction  Elastic embedding  Visualization  Single-cell RNA sequencing  Time series  Cell fate decisions  Gene expression pattern  Oscillation  In-group proportion  
A remark on copy number variation detection methods 期刊论文
PLOS ONE, 2018, 卷号: 13, 期号: 4, 页码: 11
Authors:  Li, Shuo;  Dou, Xialiang;  Gao, Ruiqi;  Ge, Xinzhou;  Qian, Minping;  Wan, Lin
Favorite  |  View/Download:12/0  |  Submit date:2018/07/30