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BiTSC2: Bayesian inference of tumor clonal tree by joint analysis of single-cell SNV and CNA data 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2022, 页码: 12
作者:  Chen, Ziwei;  Gong, Fuzhou;  Wan, Lin;  Ma, Liang
收藏  |  浏览/下载:168/0  |  提交时间:2022/06/21
single-cell DNA sequencing  intra-tumor heterogeneity  single nucleotide variation  copy number alteration  Bayesian modeling  cancer evolution  
Statistical test of structured continuous trees based on discordance matrix 期刊论文
BIOINFORMATICS, 2019, 卷号: 35, 期号: 23, 页码: 4962-4970
作者:  Bai, Xiangqi;  Ma, Liang;  Wan, Lin
收藏  |  浏览/下载:133/0  |  提交时间:2020/05/24
Multi-scale analysis of schizophrenia risk genes, brain structure, and clinical symptoms reveals integrative clues for subtyping schizophrenia patients 期刊论文
JOURNAL OF MOLECULAR CELL BIOLOGY, 2019, 卷号: 11, 期号: 8, 页码: 678-687
作者:  Ma, Liang;  Rolls, Edmund T.;  Liu, Xiuqin;  Liu, Yuting;  Jiao, Zeyu;  Wang, Yue;  Gong, Weikang;  Ma, Zhiming;  Gong, Fuzhou;  Wan, Lin
收藏  |  浏览/下载:218/0  |  提交时间:2020/05/24
Schizophrenia  PANSS  multi-scale analysis  hot cluster  grey matter volume  pathway  
DensityPath: an algorithm to visualize and reconstruct cell state-transition path on density landscape for single-cell RNA sequencing data 期刊论文
BIOINFORMATICS, 2019, 卷号: 35, 期号: 15, 页码: 2593-2601
作者:  Chen, Ziwei;  An, Shaokun;  Bai, Xiangqi;  Gong, Fuzhou;  Ma, Liang;  Wan, Lin
收藏  |  浏览/下载:193/0  |  提交时间:2020/01/10
TSEE: an elastic embedding method to visualize the dynamic gene expression patterns of time series single-cell RNA sequencing data 期刊论文
BMC GENOMICS, 2019, 卷号: 20, 页码: 16
作者:  An, Shaokun;  Ma, Liang;  Wan, Lin
收藏  |  浏览/下载:193/0  |  提交时间:2019/10/28
Nonlinear dimensionality reduction  Elastic embedding  Visualization  Single-cell RNA sequencing  Time series  Cell fate decisions  Gene expression pattern  Oscillation  In-group proportion