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Modes of genetic adaptations underlying functional innovations in the rumen 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2020, 页码: 21
作者:  Pan, Xiangyu;  Cai, Yudong;  Li, Zongjun;  Chen, Xianqing;  Heller, Rasmus;  Wang, Nini;  Wang, Yu;  Zhao, Chen;  Wang, Yong;  Xu, Han;  Li, Songhai;  Li, Ming;  Li, Cunyuan;  Hu, Shengwei;  Li, Hui;  Wang, Kun;  Chen, Lei;  Wei, Bin;  Zheng, Zhuqing;  Fu, Weiwei;  Yang, Yue;  Zhang, Tingting;  Hou, Zhuoting;  Yan, Yueyang;  Lv, Xiaoyang;  Sun, Wei;  Li, Xinyu;  Huang, Shisheng;  Liu, Lixiang;  Mao, Shengyong;  Liu, Wenqing;  Hua, Jinlian;  Li, Zhipeng;  Zhang, Guojie;  Chen, Yulin;  Wang, Xihong;  Qiu, Qiang;  Dalrymple, Brian P.;  Wang, Wen;  Jiang, Yu
收藏  |  浏览/下载：195/0  |  提交时间：2021/01/14
rumen innovations  comparative transcriptomics  comparative genomics  evo-devo  evolution of organs  
Probe Efficient Feature Representation of Gapped K-mer Frequency Vectors from Sequences Using Deep Neural Networks 期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2020, 卷号: 17, 期号: 2, 页码: 657-667
作者:  Cao, Zhen;  Zhang, Shihua
收藏  |  浏览/下载：179/0  |  提交时间：2020/05/24
DNA  Bioinformatics  Kernel  Feature extraction  Support vector machines  Genomics  Task analysis  Bioinformatics  machine learning  gapped k-mer  deep neural network  transcription factor binding site prediction  
Prediction of Driver Modules via Balancing Exclusive Coverages of Mutations in Cancer Samples 期刊论文
ADVANCED SCIENCE, 2019, 卷号: 6, 期号: 4, 页码: 9
作者:  Gao, Bo;  Zhao, Yue;  Li, Yang;  Liu, Juntao;  Wang, Lushan;  Li, Guojun;  Su, Zhengchang
收藏  |  浏览/下载：196/0  |  提交时间：2019/04/02
cancer genomics  coverage  driver modules  exclusivity  signaling networks  
Matrix Integrative Analysis (MIA) of Multiple Genomic Data for Modular Patterns 期刊论文
FRONTIERS IN GENETICS, 2018, 卷号: 9, 页码: 12
作者:  Chen, Jinyu;  Zhang, Shihua
收藏  |  浏览/下载：175/0  |  提交时间：2018/07/30
bioinformatics  multi-dimensional genomics  matrix integrative analysis  data integration  module discovery  non-negative matrix factorization (NMF)  partial least squares (PLS)  
The Discovery of Mutated Driver Pathways in Cancer: Models and Algorithms 期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2018, 卷号: 15, 期号: 3, 页码: 988-998
作者:  Zhang, Junhua;  Zhang, Shihua
收藏  |  浏览/下载：205/0  |  提交时间：2018/07/30
Bioinformatics  cancer genomics  driver gene  driver pathway  mutual exclusivity  co-occurring mutation  
Comparative pan-cancer DNA methylation analysis reveals cancer common and specific patterns 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2017, 卷号: 18, 期号: 5, 页码: 761-773
作者:  Yang, Xiaofei;  Gao, Lin;  Zhang, Shihua
收藏  |  浏览/下载：136/0  |  提交时间：2018/07/30
cancer genomics  DNA-methylation  pan-cancer study  bioinformatics  
Integrative cancer genomics: models, algorithms and analysis 期刊论文
FRONTIERS OF COMPUTER SCIENCE, 2017, 卷号: 11, 期号: 3, 页码: 392-406
作者:  Chen, Jinyu;  Zhang, Shihua
收藏  |  浏览/下载：131/0  |  提交时间：2018/07/30
cancer genomics  model  algorithm  data integration  bioinformatics  computational biology  
Bridging protein local structures and protein functions 期刊论文
AMINO ACIDS, 2008, 卷号: 35, 期号: 3, 页码: 627-650
作者:  Liu, Zhi-Ping;  Wu, Ling-Yun;  Wang, Yong;  Zhang, Xiang-Sun;  Chen, Luonan
收藏  |  浏览/下载：131/0  |  提交时间：2018/07/30
functional genomics  functional motifs  local structures  protein function prediction  
Analysis of protein surface patterns by pocket similarity network 期刊论文
PROTEIN AND PEPTIDE LETTERS, 2008, 卷号: 15, 期号: 5, 页码: 448-455
作者:  Liu, Zhi-Ping;  Wu, Ling-Yun;  Wang, Yong;  Zhang, Xiang-Sun;  Chen, Luonan
收藏  |  浏览/下载：157/0  |  提交时间：2018/07/30
protein surface pattern  pocket similarity  complex network  functional genomics  systems biology