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Interaction-based transcriptome analysis via differential network inference 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2022, 页码: 11
作者:  Leng, Jiacheng;  Wu, Ling-Yun
收藏  |  浏览/下载：45/0  |  提交时间：2023/02/07
differential network inference  differential expression analysis  interaction-based transcriptome analysis  
BiTSC2: Bayesian inference of tumor clonal tree by joint analysis of single-cell SNV and CNA data 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2022, 页码: 12
作者:  Chen, Ziwei;  Gong, Fuzhou;  Wan, Lin;  Ma, Liang
收藏  |  浏览/下载：155/0  |  提交时间：2022/06/21
single-cell DNA sequencing  intra-tumor heterogeneity  single nucleotide variation  copy number alteration  Bayesian modeling  cancer evolution  
hDirect-MAP: projection-free single-cell modeling of response to checkpoint immunotherapy 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2022, 卷号: 23, 期号: 2, 页码: 16
作者:  Lu, Yong;  Xue, Gang;  Zheng, Ningbo;  Han, Kun;  Yang, Wenzhong;  Wang, Rui-Sheng;  Wu, Lingyun;  Miller, Lance D.;  Pardee, Timothy;  Triozzi, Pierre L.;  Lo, Hui-Wen;  Watabe, Kounosuke;  Wong, Stephen T. C.;  Pasche, Boris C.;  Zhang, Wei;  Jin, Guangxu
收藏  |  浏览/下载：118/0  |  提交时间：2023/02/07
single-cell RNA sequencing (scRNA-seq)  single-cell mass cytometry (CyTOF)  Pareto optimization  projection-free single-cell modeling  response to immune checkpoint blockade  
Disease category-specific annotation of variants using an ensemble learning framework 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2022, 卷号: 23, 期号: 1, 页码: 15
作者:  Cao, Zhen;  Huang, Yanting;  Duan, Ran;  Jin, Peng;  Qin, Zhaohui S.;  Zhang, Shihua
收藏  |  浏览/下载：108/0  |  提交时间：2022/06/21
complex disease  disease category  functional annotation  non-coding variant  ensemble learning  
MIMIC: an optimization method to identify cell type-specific marker panel for cell sorting 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2021, 卷号: 22, 期号: 6, 页码: 14
作者:  Zou, Meng;  Duren, Zhana;  Yuan, Qiuyue;  Li, Henry;  Hutchins, Andrew Paul;  Wong, Wing Hung;  Wang, Yong
收藏  |  浏览/下载：135/0  |  提交时间：2022/04/02
cell type-specific marker  TFs  surface markers  dimension reduction  hierarchical topology  
Joint reconstruction of cis-regulatory interaction networks across multiple tissues using single-cell chromatin accessibility data 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2021, 卷号: 22, 期号: 3, 页码: 15
作者:  Dong, Kangning;  Zhang, Shihua
收藏  |  浏览/下载：111/0  |  提交时间：2022/04/02
cis-regulatory interaction networks  single-cell ATAC-seq  Gaussian graphical LASSO  
A survey and systematic assessment of computational methods for drug response prediction 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2021, 卷号: 22, 期号: 1, 页码: 232-246
作者:  Chen, Jinyu;  Zhang, Louxin
收藏  |  浏览/下载：179/0  |  提交时间：2021/06/01
Drug response prediction  regression model  low rank matrix factorization based approach  Bayesian inference  deep learning  benchmark  
Discovering cooperative biomarkers for heterogeneous complex disease diagnoses 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2019, 卷号: 20, 期号: 1, 页码: 89-101
作者:  Sun, Duanchen;  Ren, Xianwen;  Ari, Eszter;  Korcsmaros, Tamas;  Csermely, Peter;  Wu, Ling-Yun
收藏  |  浏览/下载：283/0  |  提交时间：2019/03/05
heterogeneous diseases  cancer biomarker  network-based  cooperative biomarker  gene expression  
Comparative pan-cancer DNA methylation analysis reveals cancer common and specific patterns 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2017, 卷号: 18, 期号: 5, 页码: 761-773
作者:  Yang, Xiaofei;  Gao, Lin;  Zhang, Shihua
收藏  |  浏览/下载：136/0  |  提交时间：2018/07/30
cancer genomics  DNA-methylation  pan-cancer study  bioinformatics