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Biomarker interaction selection and disease detection based on multivariate gain ratio 期刊论文
BMC BIOINFORMATICS, 2022, 卷号: 23, 期号: 1, 页码: 16
作者:  Chu, Xiao;  Jiang, Mao;  Liu, Zhuo-Jun
收藏  |  浏览/下载：51/0  |  提交时间：2023/02/07
Multivariate gain ratio  Biomarker interaction  Disease detection  
Group testing can improve the cost-efficiency of prospective-retrospective biomarker studies 期刊论文
BMC MEDICAL RESEARCH METHODOLOGY, 2021, 卷号: 21, 期号: 1, 页码: 10
作者:  Zhang, Wei;  Zhang, Zhiwei;  Krushkal, Julia;  Liu, Aiyi
收藏  |  浏览/下载：133/0  |  提交时间：2021/04/26
Biomarker study design  Cost-efficiency  Group testing  Pooling  Two-phase sampling  
Prediction of enhancer-promoter interactions using the cross-cell type information and domain adversarial neural network 期刊论文
BMC BIOINFORMATICS, 2020, 卷号: 21, 期号: 1, 页码: 16
作者:  Jing, Fang;  Zhang, Shao-Wu;  Zhang, Shihua
收藏  |  浏览/下载：139/0  |  提交时间：2021/01/14
Enhancer–  promoter interactions  Cell line  Convolutional neural network  Transfer learning  Gradient reversal layer  
Prim-O-glucosylcimifugin enhances the antitumour effect of PD-1 inhibition by targeting myeloid-derived suppressor cells 期刊论文
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2019, 卷号: 7, 期号: 1, 页码: 15
作者:  Gao, Wanfeng;  Zhang, Xiaoyun;  Yang, Wendong;  Dou, Daolei;  Zhang, Heng;  Tang, Yuanhao;  Zhong, Weilong;  Meng, Jing;  Bai, Yun;  Liu, Yanrong;  Yang, Lan;  Chen, Shuang;  Liu, Huijuan;  Yang, Cheng;  Sun, Tao
收藏  |  浏览/下载：155/0  |  提交时间：2020/01/10
Prim-O-glucosylcimifugin  Myeloid-derived suppressor cells  Proliferation  Metabolism  PD-1 inhibitor  
The cis-trans binding strength defined by motif frequencies facilitates statistical inference of transcriptional regulation 期刊论文
BMC BIOINFORMATICS, 2019, 卷号: 20, 页码: 11
作者:  Feng, Yance;  Zhang, Sheng;  Li, Liang;  Li, Lei M.
收藏  |  浏览/下载：154/0  |  提交时间：2019/10/28
BASE  Statistical inference  Transcriptional regulation  PUFA  DHA  EPA  Binding strength  
Systems biology intertwines with single cell and AI 期刊论文
BMC BIOINFORMATICS, 2019, 卷号: 20, 页码: 3
作者:  Wang, Yong;  Zhang, Xiang-Sun;  Chen, Luonan
收藏  |  浏览/下载：198/0  |  提交时间：2019/10/28
Systems biology  Network  Data integration  
TSEE: an elastic embedding method to visualize the dynamic gene expression patterns of time series single-cell RNA sequencing data 期刊论文
BMC GENOMICS, 2019, 卷号: 20, 页码: 16
作者:  An, Shaokun;  Ma, Liang;  Wan, Lin
收藏  |  浏览/下载：182/0  |  提交时间：2019/10/28
Nonlinear dimensionality reduction  Elastic embedding  Visualization  Single-cell RNA sequencing  Time series  Cell fate decisions  Gene expression pattern  Oscillation  In-group proportion  
Integrating random walk and binary regression to identify novel miRNA-disease association 期刊论文
BMC BIOINFORMATICS, 2019, 卷号: 20, 页码: 13
作者:  Niu, Ya-Wei;  Wang, Guang-Hui;  Yan, Gui-Ying;  Chen, Xing
收藏  |  浏览/下载：188/0  |  提交时间：2019/03/05
microRNA  Disease  miRNA-disease association  Random walk  Binary regression  
Reveal cell type-specific regulatory elements and their characterized histone code classes via a hidden Markov model 期刊论文
BMC GENOMICS, 2018, 卷号: 19, 页码: 13
作者:  Wang, Can;  Zhang, Shihua
收藏  |  浏览/下载：244/0  |  提交时间：2019/01/11
Epigenomics  Cell type-specific regulatory elements  Hidden Markov model  Histone modification  
Revealing transcription factor and histone modification co-localization and dynamics across cell lines by integrating ChIP-seq and RNA-seq data 期刊论文
BMC GENOMICS, 2018, 卷号: 19, 页码: 16
作者:  Zhang, Lirong;  Xue, Gaogao;  Liu, Junjie;  Li, Qianzhong;  Wang, Yong
收藏  |  浏览/下载：268/0  |  提交时间：2019/01/11
Transcription factor  Histone modification  Co-localization  Dynamics