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MKRMDA: multiple kernel learning-based Kronecker regularized least squares for MiRNA-disease association prediction 期刊论文
JOURNAL OF TRANSLATIONAL MEDICINE, 2017, 卷号: 15, 页码: 14
作者:  Chen, Xing;  Niu, Ya-Wei;  Wang, Guang-Hui;  Yan, Gui-Ying
收藏  |  浏览/下载:169/0  |  提交时间:2018/07/30
miRNA  Disease  miRNA-disease association  Multiple kernel learning  Kronecker regularized least squares  
Prediction of microbe-disease association from the integration of neighbor and graph with collaborative recommendation model 期刊论文
JOURNAL OF TRANSLATIONAL MEDICINE, 2017, 卷号: 15, 页码: 11
作者:  Huang, Yu-An;  You, Zhu-Hong;  Chen, Xing;  Huang, Zhi-An;  Zhang, Shanwen;  Yan, Gui-Ying
收藏  |  浏览/下载:133/0  |  提交时间:2018/07/30
NetGen: a novel network-based probabilistic generative model for gene set functional enrichment analysis 期刊论文
BMC SYSTEMS BIOLOGY, 2017, 卷号: 11, 页码: 14
作者:  Sun, Duanchen;  Liu, Yinliang;  Zhang, Xiang-Sun;  Wu, Ling-Yun
收藏  |  浏览/下载:134/0  |  提交时间:2018/07/30
Gene ontology  Enrichment analysis  Network-based probabilistic generative model  Integer programming  Complex diseases  
Hybrid method to solve HP model on 3D lattice and to probe protein stability upon amino acid mutations 期刊论文
BMC SYSTEMS BIOLOGY, 2017, 卷号: 11, 页码: 13
作者:  Guo, Yuzhen;  Tao, Fengying;  Wu, Zikai;  Wang, Yong
收藏  |  浏览/下载:160/0  |  提交时间:2018/07/30
Protein structure prediction  HP model  3D lattice  Particle swarm optimization  Protein stability  
Understanding biological systems through the lens of data 期刊论文
BMC SYSTEMS BIOLOGY, 2017, 卷号: 11, 页码: 2
作者:  Wang, Yong;  Zhang, Xiang-Sun;  Chen, Luonan
收藏  |  浏览/下载:152/0  |  提交时间:2018/07/30
GATE: an efficient procedure in study of pleiotropic genetic associations 期刊论文
BMC GENOMICS, 2017, 卷号: 18, 页码: 15
作者:  Zhang, Wei;  Yang, Liu;  Tang, Larry L.;  Liu, Aiyi;  Mills, James L.;  Sun, Yuanchang;  Li, Qizhai
收藏  |  浏览/下载:136/0  |  提交时间:2018/07/30
Pleiotropic genetic associations  Principal component analysis  Power  Biomedical study  
Estimating Phred scores of Illumina base calls by logistic regression and sparse modeling 期刊论文
BMC BIOINFORMATICS, 2017, 卷号: 18, 页码: 14
作者:  Zhang, Sheng;  Wang, Bo;  Wan, Lin;  Li, Lei M.
收藏  |  浏览/下载:138/0  |  提交时间:2018/07/30
Base-calling  Logistic regression  Quality score  L-1 regularization  AIC  BIC  Empirical discrimination power  
Structure alignment-based classification of RNA-binding pockets reveals regional RNA recognition motifs on protein surfaces 期刊论文
BMC BIOINFORMATICS, 2017, 卷号: 18, 页码: 13
作者:  Liu, Zhi-Ping;  Liu, Shutang;  Chen, Ruitang;  Huang, Xiaopeng;  Wu, Ling-Yun
收藏  |  浏览/下载:147/0  |  提交时间:2018/07/30
RNA-binding pocket  Local structure classification  Structural alignment  Network clustering  Structure motif