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Network diffusion for scalable embedding of massive single-cell ATAC-seq data 期刊论文
SCIENCE BULLETIN, 2021, 卷号: 66, 期号: 22, 页码: 2271-2276
作者:  Dong, Kangning;  Zhang, Shihua
收藏  |  浏览/下载:114/0  |  提交时间:2022/04/02
Approximate distance correlation for selecting highly interrelated genes across datasets 期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2021, 卷号: 17, 期号: 11, 页码: 18
作者:  Shen, Qunlun;  Zhang, Shihua
收藏  |  浏览/下载:115/0  |  提交时间:2022/04/02
Joint reconstruction of cis-regulatory interaction networks across multiple tissues using single-cell chromatin accessibility data 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2021, 卷号: 22, 期号: 3, 页码: 15
作者:  Dong, Kangning;  Zhang, Shihua
收藏  |  浏览/下载:113/0  |  提交时间:2022/04/02
cis-regulatory interaction networks  single-cell ATAC-seq  Gaussian graphical LASSO  
Bayesian Joint Matrix Decomposition for Data Integration with Heterogeneous Noise 期刊论文
IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE, 2021, 卷号: 43, 期号: 4, 页码: 1184-1196
作者:  Zhang, Chihao;  Zhang, Shihua
收藏  |  浏览/下载:175/0  |  提交时间:2021/04/26
Matrix decomposition  Bayes methods  Data integration  Inference algorithms  Data models  Data mining  Gaussian distribution  Bayesian methods  matrix decomposition  data integration  variational Bayesian inference  maximum a posterior  
Towards understanding residual and dilated dense neural networks via convolutional sparse coding 期刊论文
NATIONAL SCIENCE REVIEW, 2021, 卷号: 8, 期号: 3, 页码: 13
作者:  Zhang, Zhiyang;  Zhang, Shihua
收藏  |  浏览/下载:146/0  |  提交时间:2021/10/26
convolutional neural network  convolutional sparse coding  residual neural network  mixed-scale dense neural network  dilated convolution  dense connection  
A Novel Sparse Graph-Regularized Singular Value Decomposition Model and Its Application to Genomic Data Analysis 期刊论文
IEEE TRANSACTIONS ON NEURAL NETWORKS AND LEARNING SYSTEMS, 2021, 页码: 15
作者:  Min, Wenwen;  Wan, Xiang;  Chang, Tsung-Hui;  Zhang, Shihua
收藏  |  浏览/下载:135/0  |  提交时间:2022/04/02
Gene expression  Biology  Biological system modeling  Principal component analysis  Mathematical model  Data models  Big Data  Absolute-valued graph regularization  graph regularization  sparse learning  structured sparse singular value decomposition (SVD)  
3D Genome of macaque fetal brain reveals evolutionary innovations during primate corticogenesis 期刊论文
CELL, 2021, 卷号: 184, 期号: 3, 页码: 723-+
作者:  Luo, Xin;  Liu, Yuting;  Dang, Dachang;  Hu, Ting;  Hou, Yingping;  Meng, Xiaoyu;  Zhang, Fengyun;  Li, Tingting;  Wang, Can;  Li, Min;  Wu, Haixu;  Shen, Qiushuo;  Hu, Yan;  Zeng, Xuerui;  He, Xiechao;  Yan, Lanzhen;  Zhang, Shihua;  Li, Cheng;  Su, Bing
收藏  |  浏览/下载:160/0  |  提交时间:2021/06/01
Group-Sparse SVD Models via L-1- and L-0-norm Penalties and their Applications in Biological Data 期刊论文
IEEE TRANSACTIONS ON KNOWLEDGE AND DATA ENGINEERING, 2021, 卷号: 33, 期号: 2, 页码: 536-550
作者:  Min, Wenwen;  Liu, Juan;  Zhang, Shihua
收藏  |  浏览/下载:151/0  |  提交时间:2021/04/26
Sparse SVD  low-rank matrix decomposition  group-sparse penalty  overlapping group-sparse penalty  coordinate descent method  alternating direction method of multipliers (ADMM)  data mining  
Imputing single-cell RNA-seq data by considering cell heterogeneity and prior expression of dropouts 期刊论文
JOURNAL OF MOLECULAR CELL BIOLOGY, 2021, 卷号: 13, 期号: 1, 页码: 29-40
作者:  Zhang, Lihua;  Zhang, Shihua
收藏  |  浏览/下载:125/0  |  提交时间:2021/10/26
single-cell RNA-seq  dropout  imputation  low-rank  systems biology  
An Integrative Framework for Combining Sequence and Epigenomic Data to Predict Transcription Factor Binding Sites Using Deep Learning 期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2021, 卷号: 18, 期号: 1, 页码: 355-364
作者:  Jing, Fang;  Zhang, Shao-Wu;  Cao, Zhen;  Zhang, Shihua
收藏  |  浏览/下载:160/0  |  提交时间:2021/04/26
Bioinformatics  machine learning  transcription factors binding sites  convolutional neural networks  DNA accessibility  histone modification