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Time course regulatory analysis based on paired expression and chromatin accessibility data 期刊论文
GENOME RESEARCH, 2020, 卷号: 30, 期号: 4, 页码: 622-634
作者:  Duren, Zhana;  Chen, Xi;  Xin, Jingxue;  Wang, Yong;  Wong, Wing Hung
收藏  |  浏览/下载：177/0  |  提交时间：2020/06/30
ELF: Extract Landmark Features By Optimizing Topology Maintenance, Redundancy, and Specificity 期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2020, 卷号: 17, 期号: 2, 页码: 411-421
作者:  Feng, Zhan-Ying;  Wang, Yong
收藏  |  浏览/下载：184/0  |  提交时间：2020/05/24
Feature extraction  Topology  Ground penetrating radar  Geophysical measurement techniques  Redundancy  Maintenance engineering  Manganese  Feature selection  topology maintenance  optimization  single cell  
DC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data 期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 11
作者:  Zeng, Wanwen;  Chen, Xi;  Duren, Zhana;  Wang, Yong;  Jiang, Rui;  Wong, Wing Hung
收藏  |  浏览/下载：182/0  |  提交时间：2020/01/10
Hierarchical graphical model reveals HFR1 bridging circadian rhythm and flower development in Arabidopsis thaliana 期刊论文
NPJ SYSTEMS BIOLOGY AND APPLICATIONS, 2019, 卷号: 5, 页码: 11
作者:  Duren, Zhana;  Wang, Yaling;  Wang, Jiguang;  Zhao, Xing-Ming;  Lv, Le;  Li, Xiaobo;  Liu, Jingdong;  Zhu, Xin-Guang;  Chen, Luonan;  Wang, Yong
收藏  |  浏览/下载：167/0  |  提交时间：2020/05/24
Systems biology intertwines with single cell and AI 期刊论文
BMC BIOINFORMATICS, 2019, 卷号: 20, 页码: 3
作者:  Wang, Yong;  Zhang, Xiang-Sun;  Chen, Luonan
收藏  |  浏览/下载：200/0  |  提交时间：2019/10/28
Systems biology  Network  Data integration  
Genetic Load and Potential Mutational Meltdown in Cancer Cell Populations 期刊论文
MOLECULAR BIOLOGY AND EVOLUTION, 2019, 卷号: 36, 期号: 3, 页码: 541-552
作者:  Zhang, Yuezheng;  Li, Yawei;  Li, Tao;  Shen, Xu;  Zhu, Tianqi;  Tao, Yong;  Li, Xueying;  Wang, Di;  Ma, Qin;  Hu, Zheng;  Liu, Jialin;  Ruan, Jue;  Cai, Jun;  Wang, Hurng-Yi;  Lu, Xuemei
收藏  |  浏览/下载：253/0  |  提交时间：2020/01/10
genetic load  Muller's ratchet  HeLa cell line  copy number variation  
TFAP2C-and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment 期刊论文
CELL STEM CELL, 2019, 卷号: 24, 期号: 2, 页码: 271-+
作者:  Li, Lingjie;  Wang, Yong;  Torkelson, Jessica L.;  Shankar, Gautam;  Pattison, Jillian M.;  Zhen, Hanson H.;  Fang, Fengqin;  Duren, Zhana;  Xin, Jingxue;  Gaddam, Sadhana;  Melo, Sandra P.;  Piekos, Samantha N.;  Li, Jiang;  Liaw, Eric J.;  Chen, Lang;  Li, Rui;  Wernig, Marius;  Wong, Wing H.;  Chang, Howard Y.;  Oro, Anthony E.
收藏  |  浏览/下载：282/0  |  提交时间：2019/03/11
Revealing transcription factor and histone modification co-localization and dynamics across cell lines by integrating ChIP-seq and RNA-seq data 期刊论文
BMC GENOMICS, 2018, 卷号: 19, 页码: 16
作者:  Zhang, Lirong;  Xue, Gaogao;  Liu, Junjie;  Li, Qianzhong;  Wang, Yong
收藏  |  浏览/下载：272/0  |  提交时间：2019/01/11
Transcription factor  Histone modification  Co-localization  Dynamics  
Integrative analysis of single-cell genomics data by coupled nonnegative matrix factorizations 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 卷号: 115, 期号: 30, 页码: 7723-7728
作者:  Duren, Zhana;  Chen, Xi;  Zamanighomi, Mahdi;  Zeng, Wanwen;  Satpathy, Ansuman T.;  Chang, Howard Y.;  Wang, Yong;  Wong, Wing Hung
收藏  |  浏览/下载：178/0  |  提交时间：2019/12/13
coupled clustering  NMF  single-cell genomic data  
Modeling gene regulation from paired expression and chromatin accessibility data 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, 卷号: 114, 期号: 25, 页码: E4914-E4923
作者:  Duren, Zhana;  Chen, Xi;  Jiang, Rui;  Wang, Yong;  Wong, Wing Hung
收藏  |  浏览/下载：159/0  |  提交时间：2018/07/30
gene regulation  transcription factor  regulatory element  chromatin regulator  chromatin activity